There is evidence of clinically important drug-drug interactions between cannabis or cannabinoids and the following medications: chlorpromazine, clobazam, clozapine, CNS depressants (e.g., barbiturates, benzodiazepines), disulfiram,
hexobarbital, hydrocortisone, ketoconazole, MAO inhibitors, phenytoin, protease inhibitors (indinavir, nelfinavir), theophylline, tricyclic antidepressants and warfarin.