Over 30% of known enzymes are metalloenzymes, covering all major enzyme classes: oxidoreductases, transferases,
hydrolases, lyases, isomerases, and ligases.
In addition to the clinical and pre-clinical programmes targeting MGLL, Abide has a rich pipeline of inhibitors targeting other serine
hydrolases that may be pursued as future novel treatments to improve the quality of life for patients living with neurological and/or psychiatric disorders.
The team used a library of about 100 such compounds, all known to inhibit enzymes called serine
hydrolases in mammals.
The study opines that among the various enzymes used in the food industry,
hydrolases continue to account for the highest demand.
On the basis of reaction end products and substrate specificity five types of pullulanases have been reported till now, among them two are called pullulanases (pullulanase types I and pullulanase type II) while the other three are known as pullulan
hydrolases (pullulan
hydrolase types I, pullulan
hydrolase type II and pullulan
hydrolase type III).
Wilkinson, "Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal
hydrolases," Biochemistry, vol.
Chaetomium thermophilum is a thermophilic fungus expressed a series of glycoside
hydrolases. Genome sequence analysis of C.
Considering that poultry feeds consist mainly of cereal grains which are rich in nonstarch polysaccharides including xylans and arabinoxylans, microorganisms producing nonstarch polysaccharide
hydrolases including xylanase should be abundant in chicken intestine.
Genes encoding bile salt
hydrolases and conjugated bile salt transporters in Lactobacillus johnsonii 100-100 and other Lactobacillus species.