interleukin

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in·ter·leu·kin

 (ĭn′tər-lo͞o′kĭn)
n.
Any of various small proteins that are produced by a variety of cell types, especially T cells and other white blood cells, and that regulate many aspects of inflammation and the immune response, including stimulating the production of white blood cells and platelets.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

interleukin

(ˌɪntəˈluːkɪn)
n
(Biochemistry) a substance extracted from white blood cells that stimulates their activity against infection and may be used to combat some forms of cancer
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

in•ter•leu•kin

(ˈɪn tərˌlu kɪn)
n.
any of a family of small proteins that participate in the body's defense system, esp. by promoting the growth and activation of white blood cells.
[1979; inter- + leuk (ocyte) + -in1; so called because such proteins act as agents of communication between different populations of leukocytes]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.interleukin - any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)
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References in periodicals archive
At a preinjury baseline, six, and 24 to 48 hours postinjury, and about eight, 15, and 45 days after concussion, serum levels of IL-6, IL-1?, IL-10, tumor necrosis factor, C-reactive protein, interferon-?, and IL-1RA were measured.
o IL-1?, IL-1?, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12p70, IL-13, IL-15, IL-17, IL-23, IFN-?, TNF-?, TNF-?
In spite of increasing number of diabetes and rapid progress of science and technologies in its management and treatment, there has not been much studies on IL-6 and its correlation with BMI among diabetics.
A recent study on allergic airway inflammation demonstrated that soluble ST2 blocked IL-33 signaling.[12] In addition, an in vitro study demonstrated that soluble ST2 could suppress lipopolysaccharide (LPS)-induced IL-6 production in THP-1 cells,[7] and whether this function was restricted to the inhibition of the IL-33/ST2 axis was unknown.
The production of reactive oxygen species (ROS) is required to induce the microbicidal activity mediated by vitamin D and cathelicidin, and cathelicidin enhances the production of ROS and proinflammatory cytokines, such as TNF-[alpha], IL-8, and IL-6 [99].
IL-6 acts by Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway and contributes to insulin resistance by inhibiting phosphorylation of insulin receptor as well as causing proteasomal degradation of insulin receptor substrate (IRS) 1 and 2.5 IL-6 itself causes rise in serum insulin levels by augmenting release of Glucagon-like peptide (GLP) from intestinal cells as well as pancreatic alpha cells aggravating the hyperinsulinism in T2DM.6
The interaction of IL-34 and CFR-1R significantly enhanced IL-6 production of FLS possibly through JNK/P38/NF-[kappa]B signaling pathway.
Objective: To investigate the effects of varying Warfarin doses on IL-6 and COX-2.
Sandwich ELISA was used for the estimation of circulatory IL-6.
Interleukin-6 (IL-6) is an important cytokine of Tand B-lymphocytes the level of which indicates the status of immune function.23 Thus the levels of IL-6 and its soluble receptor (IL-6R) in human body can often be used as indices for the diagnosis and detection of autoimmune diseases.
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