Locus, heterozygosity (He) and fixation index (FST) for each of 17 genotyped SNPs Locus Het [F.sub.ST] p value IL-3 0.292 0.0087 0.526 IL1-[alpha] 0.487 -0.005 0.251 IL1-[alpha] 0.362 -0.001 0.354 IL1-[beta] 0.479 -0.006 0.236 IL1-[beta] 0.481 -0.006 0.244 IL1-[beta] 0.412 -0.001 0.334 IL-4 0.429 0.04 0.884 IL-8 0.517 0.057 0.92 IL-8 0.534 0.013 0.589 IL-31 0.497 -0.005 0.251 IL-33 0.492 -0.009 0.168 IL-33 0.201 0.06 0.951 IL-33 0.408 0.013 0.606 IL-32(1158) 0.438 0.043 0.893 IL-32(2017) 0.465 -0.008 0.154 IL-32(7638) 0.485 0.022 0.735 IL-32(9375) 0.487 0.0861 0.985* SNP, single nucleotide polymorphisms;
IL32, interleukin.
Genes expressed more highly in OECs were Jagged 1 (JAG1), JAG2, placental growth factor (PGF), endothelial cell-specific molecule 1 (ESM1), neurite growth-promoting factor 2 (MDK), inhibin beta A (INHBA), growth differentiation factor-3 (GDF3), pre-B-cell colony-enhancing factor 1 (PBEF1), endothelin 1 (EDN1), interleukin 32 (
IL32), heparin-binding EGF-like growth factor (HBEGF), chemokine (C-X-C motif) ligand 1 (CXCL1), chemokine (C-C motif) ligand 2 (CCL2), CCL14, CCL15, bone morphogenetic protein 2 (BMP2), BMP4, and BMP6, whereas genes expressed more highly in MSCs were wingless-type MMTV integration site family, member 5A (WNT5A), CXCL5, vascular endothelial growth factor (VEGF), CCL20, angiopoietin 1 (ANGPT1), growth differentiation factor 5 (GDF5), and WNT5B (Figure 7).