"We were now able to show that Par3 has a direct influence on the homeostasis of the skin by controlling the mechanical properties of
keratinocytes, the main skin epithelial cell," said Iden.
As a matter of fact, skin pigmentation is the consequence of the transfer of black bodies called melanosomes from the melanocytes in the epidermis to the surrounding
keratinocytes. Melanocytes are cells with a characteristic star-like form.
The epidermis is the outermost layer, mainly composed of
keratinocytes, organized into four major layers at progressive differentiation stages: basal, spinous, granular, and cornified layers (Candi et al., 2005; Bouwstra and Ponec, 2006; Dellambra and Dimri, 2009; Fuchs, 2016).
To investigate collagen metabolism in
keratinocytes and fibroblasts co-culture under pressure, and study the role of IL-1[alpha] and MMP-3 in terms of regulating fibroblasts-keratinocytes collagen metabolism with pressure.
An elective way to deal with address the disadvantages by skin autografts is to graft in vitro-expanded epithelial
keratinocytes, utilizing a solid technique for refined human epidermal
keratinocytes in the coherent layers of skin.
Herein we describe a case and dermoscopic findings of an unusual photodermatosis with lichenoid pathology and necrotic
keratinocytes that was diagnosed by clinical features, dermoscopic findings, and histopathological findings.
Skin, comprised of
keratinocytes, melanocytes, and fibroblasts, is the largest organ of the human body, and it provides a protective barrier between the internal milieu and the environment (9,10).
Izpisua Belmonte and Salk Research Associate Masakazu Kurita, who has a background in plastic surgery, knew that a critical step in wound recovery was the migration -- or transplantation -- of basal
keratinocytes into wounds.
Background: Signal transducer and activator of transcription 3 (STAT3) was strongly expressed and activated in psoriatic
keratinocytes (KCs) and correlated with the severity of psoriasis.
HPV infects skin cells known as
keratinocytes before they have fully matured, or differentiated, and are still dividing into new cells.