Gilbert joined Berlex from Immunex, where his responsibilities included development and medical affairs for
Leukine and Mitoxantrone in hematology, oncology, Crohn's disease, and multiple sclerosis.
At present, L-asparaginase is available in the market with different brand names, such as ERWINASE, CLOLAR,
LEUKINE, ONCASPAR, ARR-ANON, KIDROLASE and ELSPAR.
A safety trial on the drug
Leukine already is underway at the Colorado University Anschutz Medical Campus.
Global Banking News-June 7, 2018-Partner wins US FDA's approval for
Leukine for treating Acute Radiation Syndrome
M2 EQUITYBITES-June 7, 2018-Partner wins US FDA's approval for
Leukine for treating Acute Radiation Syndrome
-PARTNER THERAPEUTICS ACQUIRES RIGHTS TO COMMERCIALISE
LEUKINE FROM SANOFI
Department of Health and Human Services, awarded Sanofi a $37.6 million contract to supply and manage inventory for
Leukine. Sanofi Genzyme is developing
Leukine for the treatment of acute radiation syndrome, a serious illness that occurs in people exposed to high doses of radiation.
Leukine, recombinant GM-CSF, is approved by the FDA (Figure 3) and functions in similar manner to Filgrastim.
There were detected seasonal variations of Ltryptophan, and the L-tryptophan / amino acids (valine,
leukine, isoleukine, tyrosine, phenylalanine) connection, by detecting their significantly lower values in spring compared to other seasons.
IL-2 directly promotes NK function, (83-85) while
Leukine induces bone marrow production of macrophages.
Niaz presented data from a study that quoted that 95% of a set of patients showed immune response to
leukine (active ingredient: sargramostim), whereas there were some others that elicited far less immunogenicity; for example, Avonex (active gradient: interferon beta-1a); 6%, and Neupogen (active ingredient: filgrastim), zero (0%).
Your doctor should also prescribe medications such as filgrastim (Neupogen), pegfilgrastim (Neulasta) or sargramostim (
Leukine) between chemotherapy cycles to quickly restore reduced white blood cell counts to normal levels to help prevent infection.