(b) Oxidized
linoleic acid supplementation led to dose dependent significant (P < 0.05) decreases in plasma hepatic lipase when compared to the plain fed group of mice.
As the most significant contributory cause,
linoleic acid (%), the greatest constituent among the twenty-four FFA fractions, was negatively correlated with visceral fat area (r = -0.411, F =17.73, p <0.0001) (Figure 1(a)), whereas it was not correlated with subcutaneous fat area.
There is a catch, though: low-cost cooking oils rich in
linoleic acid have been disappearing from grocery shelves, fueled by industry's push for plants that have been modified to produce oils higher in oleic acid.
The BMJ study found that consuming vegetable oil with
linoleic acid in place of saturated fat did indeed help participants reduce cholesterol levels.
(2010) obtained 58.06% of the total content of unsaturated fatty acids, among which oleic acid, with average of 38.29%, and
linoleic acid, with average of 13.46%.
The level of retained
linoleic acid and the production of 7-ketocholesterol in the emulsion were determined by gas chromatography and high-performance liquid chromatography, as a way to monitor the degree of oxidation.
Linoleic acid conjugated methyl ester (mixture of cis-and trans-9,11-and -10,12-octadecadienoic acid methyl esters, catalog number O5632) was purchased from Sigma-Aldrich (St Louis, MO, USA).
The findings, reported in the British Medical Journal, suggest that using vegetable oils high in
linoleic acid might be worse than using butter when it comes to preventing heart disease, though more research needs to be done on that front.
Comment: There is evidence that patients with eczema have reduced activity of the enzyme delta-6-desaturase, which plays a role in the conversion of
linoleic acid to gammalinolenic acid (GLA).
The determination of kinetic parameters for the cis-trans isomerisation of
linoleic acids in trilinolein is interesting and will reveal whether the matrix surrounding the
linoleic acid moieties play a part in affecting the kinetic parameters for the isomerisation reaction.
About 5.6 g/day conjugated
linoleic acid supplement and oral paraffin (placebo) were given to intervention and control groups respectively daily for two weeks.
Linoleic acid also helps in regenerating of new skin cells which results in removing of scars and unwanted blemishes from skin surface, ultimately one that use to treat skin with safflower oil looks younger.