(Textiles) (tr) to moisten or soak (flax, hemp, jute, etc) to promote bacterial action in order to facilitate separation of the fibres from the woody tissue by beating
[C15: of Germanic origin; related to Middle Dutch reeten, Swedish röta, German rösten; see rot1]
Offering genetic testing on the basis of a family history consistent with MEN2A, MEN2B, or FMTC does not detect all hereditary cases, emphasizing the importance of recognition of the association.
Based on her agglomeration of thyroid-related maladies, her medical team suspected something else - namely, a syndrome called multiple endocrine neoplasia, Type 2A, or MEN2a for short.
Multiple endocrine neoplasia type 2 (MEN2) syndromes are autosomally dominant clinical associations characterised by a number of tumours, including medullary thyroid carcinoma (MTC), phaeochromocytoma, thyroid C-cell hyperplasia (CCH), parathyroid tumours (MEN2A) and ganglioneuroma of the gastrointestinal tract (MEN2B).
While a number (20%) of MTCs are associated with the autosomal-dominant inherited multiple endocrine neoplasia (MEN) syndromes (specifically MEN2A and MEN2B), most (80%) cases are sporadic.
[13] Shirley Myers et al., "Progress Towards Identification of the Genotype for Multiple Endocrine Neoplasia 2A (MEN2A)." Paper presented at the annual meeting of the American Society of Human Genetics, New orleans, LA, October 12-15, 1988.
MEN2A accounts for 80% of hereditary MTC syndromes; consists of MTC in all patients, pheochromocytoma in 50% and primary hyperparathyroidism in 20-30% of patients (4).
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