mi·cro·some

(mī′krə-sōm′)

A small particle in the cytoplasm of a cell, typically consisting of fragmented endoplasmic reticulum to which ribosomes are attached.

mi′cro·so′mal (-sō′məl), mi′cro·so′mic (-sō′mĭk) adj.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

microsome

(ˈmaɪkrəʊˌsəʊm)

(Biology) any of the small particles consisting of ribosomes and fragments of attached endoplasmic reticulum that can be isolated from cells by centrifugal action

ˌmicroˈsomal adj

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

mi•cro•some

(ˈmaɪ krəˌsoʊm)

n.

a small vesicle containing fragments of ribosomes and other organelles, formed during cell breakage by centrifugation.

[1880–85]

mi`cro•so′mal, adj.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

microsome - a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNA

cytol, cytoplasm - the protoplasm of a cell excluding the nucleus; is full of proteins that control cell metabolism

granule - a tiny grain

Translations

mi·cro·some

n. microsoma, elemento fino granular del protoplasma.

English-Spanish Medical Dictionary © Farlex 2012

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References in periodicals archive

Thyroglobulin and microsome autoantibodies and their clinical significance in adult type I diabetics (in Czech).

Thyroid auto immune antibodies in children with Type-I Diabetes mellitus in relation to diabetes control

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Based upon preclinical animal liver microsome studies, this differential effect appears to be limited to rodents, and is not observed in preclinical studies with human liver microsomes.

Onconova presents data on dual inhibitor of CDK4/6 + ARK5

Volker Auwarter: I would slightly disagree, because marker identification can also be performed effectively by using prepared human liver microsome assays, which are less expensive and time-consuming.

Impact of Novel Psychoactive Substances on Clinical and Forensic Toxicology and Global Public Health

In: Microsome, Drug oxidation and chemical carcinogenesis (ed.

Effect of Inorganic Mercury on Drug Metabolizing Enzymes of Promethazine-Pretreated and Phenobarbitone-Pretreated Male Rabbit

Those associated with the endoplasmic reticulum (microsome) membrane are [P450.sub.17[alpha]], (now termed CYP17) for steroid 17,-hydroxylation and C17-C20 bond cleavage, [P450.sub.C21] (now termed CYP21) for steroid 21-hydroxylation, and 3[beta]-hydroxysteroid dehydrogenase/isomerase.

Functional zonation of the rat adrenal cortex: the development and maintenance

Serum and hepatic microsome were used to analyze lipid peroxidation.

Effects of vitamin C or E on the pro-inflammatory cytokines, heat shock protein 70 and antioxidant status in broiler chicks under summer conditions

Oui le film est violent mais ce n'est pas la violence des gangsters et des mafieux qui atteint son comble dans les affranchis...c'est la violence des rapports sociaux dans ce microsome infernal que sont les milieux de la finance.

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Salmonella / microsome fluctuation test (Ames fluctuation test).

Latest standards in the field of environmental testing

However, the distribution among the organelle fraction is clearly different as in the cuttlefish 52% was bound to the nuclei fraction whereas in the squid, 42% was bound to the microsome fraction.

Subcellular distribution of Ag, Cd, Co, Cu, Fe, Mn, Pb, and Zn in the digestive gland of the common cuttlefish Sepia officinalis

Using state-of-the-art technologies such as liver microsome testing and Caco2 cell absorption, and high-speed analytical techniques like LC/MS/MS, this triumvirate of services provides key metabolic and pharmacokinetic data used by companies as lead optimization tools.

Phoenix International