Oncovin

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Noun1.Oncovin - periwinkle plant derivative used as an antineoplastic drug (trade name Oncovin); used to treat cancer of the lymphatic system
periwinkle plant derivative - an antineoplastic drug used to treat some forms of cancer
brand, brand name, marque, trade name - a name given to a product or service
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However, the most popular therapy for advanced histiocytic sarcoma appears to be cyclophosphamide, hydroxydaunorubicin, oncovin, and prednisone.
After Pre-Chemotherapy Workup, Multidrug Chemotherapy (Etoposide, Methotrexate, Actinomycin - D, Cyclo-phosphamide, Oncovin / Vincristine) was started and the patient was regularly monitored by CBCs, LFTs, RFTs and Serum [beta] HCG.
He was planned for standard treatment of rituximab-cyclophosphamide, hydroxydaunorubicin, Oncovin, and prednisone (R-CHOP), but the patient developed upper gastrointestinal bleed and succumbed to death before starting the chemotherapy.
The patient was submitted to chemotherapy with six cycles of R-CHOP (rituximab + cyclophosphamide, hydroxydaunorubicin, oncovin, and prednisone), after surgery.
The main complaints were pain in both ears, diplopia, and restriction of inward movement of the left eye after the CHOP (Cyclophosphamide, Hydroxydaunorubicin, Oncovin, and Prednisone) treatment.
Following the diagnosis of THRLBCL, the patient was treated with R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone) given the lack of data to support use of a more aggressive regimen such as DA-R-EPOCH (dose-adjusted Rituximab, Etoposide, Prednisone, Vincristine (Oncovin), Cyclophosphamide, and Doxorubicin).
Patient was administered 6 cycles of R-CHOP (Rituximab 375 mg/[m.sup.2], Cyclophosphamide 750 mg/[m.sup.2], Doxorubicin 50 mg/[m.sup.2], Oncovin 1.4 mg/[m.sup.2], with dose of prednisolone modified to 80 mg because of her diabetes) following which her lesion resolved completely.
marneffei Antifungal treatment Amphotericin B (2 (duration, mo) weeks) and voriconazole (>5) Other opportunistic Herpes zoster infections at right occiput Clinical outcome Responded to antifungal treatment * mAb, monoclonal antibody; JAK, Janus kinase; IV, intravenous; CHOP, cyclophosphamide, hydroxydaunorubicin, oncovin, and prednisolone; MRCNS, methicillin-resistant coagulase-negative Staphylococcus; HSV, herpes simplex virus; PJP, Pneumocystis jiroveci pneumonia; MODS, multiple organ dysfunction syndrome.
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