Anatomy and physiology teach that feedback to the central nervous system comes largely from Golgi tendon organs,
Pacinian corpuscles, and Ruffini nerve endings.
In the dermis, there are Ruffini endings and
Pacinian corpuscles in a glabrous (or hairless) skin, whereas there is a complex combination of mechanoreceptors and their associated nerves and hair follicle receptors in a hairy skin [23, 24].
(2) FA mechanoreceptors can be divided into Meissner corpuscles and
Pacinian corpuscles, being the first one related to low (30 Hz) and the later one to high (200 Hz) vibration frequencies.
There are more touch and pressure receptors such as Meissner's corpuscles,
Pacinian corpuscles, Merkel's disks, and Ruffini's corpuscles under the skin of the palm than under the skin of the dorsal part of the hand.
This is consistent with the literature where PN showed typical histopathologic image of round or ovoid lobules that contain
Pacinian corpuscles embedded in myxoid stroma.
Vibration excites
Pacinian corpuscles, and these receptors convey their information through gracile and cuneate fascicles to higher centers.