Gas-phase cigarette smoke (filtered to remove particulate matter) oxidized both plasma proteins and lipids, but whole cigarette smoke oxidized only the proteins.
PlasmaCap IG has been developed utilizing Evolve's innovative PlasmaCap EBA technology, which allows for the efficient capture of plasma proteins and offers the potential of higher yields and purities.
Where it is relevant, he also talks about producing recombinant products based on plasma proteins and using a protein as a diagnostic analyte, but not using blood plasma as a source of biomarkers except in passing.
OBJECTIVE: In this study, we evaluated associations of cigarette smoking and chronic obstructive pulmonary disease (COPD) with nitrotyrosine modifications of specific plasma proteins to gain insight into the processes regulating nitrotyrosine formation.
The first generation of proteomics methodologies (particularly 2-dimensional electrophoresis) had detected about 60 plasma proteins by the early 1990s (1), and these proteins were more or less the same as those previously tabulated in Frank Putnam's reference books (The Plasma Proteins) and purified by the Behring Institute and others.
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