This industry includes establishments that produce drugs such as insulin, pramlintide and other drugs to treat diabetes, anti-thyroid drugs to treat hyperthyroidism, and other drugs to treat pituitary gland, adrenal gland and parathyroid gland disorders.
Pramlintide (Symlin; AstraZeneca, Cambridge, United Kingdom), a synthetic amylin analog, lowers the glycated hemoglobin (HbA1c) level in patients with type 1 and 2 diabetes, slows down gastric emptying, reduces appetite, and exerts favorable effects on body weight.
Hwang et al., "Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition," Neurobiology of Aging, vol.
IAPP hyposecretion is well-established in T1DM and insulin-requiring T2DM [43,45]: A synthetic IAPP, pramlintide [28-30] (pro-hIAPP) has been used for treating both T1DM and insulin-requiring T2DM together with insulin replacement for a better glycemic control [46-49].
The effect of pramlintide acetate on glycemic control and weight in patients with type 2 diabetes mellitus and in obese patients without diabetes: a systematic review and meta-analysis.
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