Pur·kin·je cell

(pûr-kĭn′jē)

A large, drop-shaped, densely branching neuron that is the characteristic cell of the cerebellar cortex.

[After Johannes Evangelista von Purkinje (1787-1869), Bohemian physiologist.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Pur•kin′je cell`

(pərˈkɪn dʒi)
n.

a large, densely branching neuron in the cerebellar cortex of the brain.

[1885–90; see Purkinje fiber]

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

Purkinje cell - a large densely branching neuron that is the characteristic cell of the cerebellar cortex

brain cell - a nerve cell in the brain

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References in periodicals archive

Using advanced imaging, the researchers went on to show that the rescue of social behaviours correlates with reversal of specific MRI-based structural changes, cellular pathology and Purkinje cell excitability.

Treatment at young age could reverse autistic behaviour in tuberous sclerosis

Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency.

Expanding the Phenotype of Homozygous KCNMA1 Mutations; Dyskinesia, Epilepsy, Intellectual Disability, Cerebellar and Corticospinal Tract Atrophy

Necropsy revealed severe pancreatic atrophy and fibrosis with regionally extensive cerebellar encephalomalacia and generalized Purkinje cell degeneration and necrosis.

Diabetes Mellitus With Concurrent Cerebellar Degeneration and Necrosis in a Domestic Goose (Anser anser domesticus)

(2016) Synaptic specializations support frequency-independent Purkinje cell output from the cerebellar cortex.

Kinetics of transmitter release at the calyx of Held synapse

They also plan to use the Purkinje cell platform to study other ASD-related genetic disorders, including Fragile X and SHANK3 mutation, and to test potential drugs.

Lab-Grown Human Cerebellar Cells Enable Study Of Autism

Objective: To study and compare the histomorphological changes induced by second generation (2G), third generation (3G) and fourth generation (4G) mobile phone electromagnetic fields on the organization of Purkinje cell layer of rat cerebellum.

EFFECT OF ELECTROMAGNETIC FIELD FROM 2G, 3G AND 4G MOBILE PHONES ON THE ORGANIZATION OF PURKINJE CELL LAYER OF RAT CEREBELLUM

DSCAM expression in cerebellar Purkinje cell layers of (C) WT and (D) APP transgenic mice (indicated by arrows).

Hippocampal overexpression of Down syndrome cell adhesion molecule in amyloid precursor protein transgenic mice

G-CSF receptors are expressed in pyramidal neurons in the cortex (mainly layers II/III and V), the Purkinje cell layer of the cerebellum, the hippocampus (hilus and CA3 field), the entorhinal cortex and the olfactory bulb.

Granulocyte colony-stimulating factor potential use in the treatment of children with cerebral palsy

Yi et al., "High [omega]3-polyunsaturated fatty acids in fat-1 mice prevent streptozotocin-induced Purkinje cell degeneration through BDNF-mediated autophagy," Scientific Reports, vol.

Accumulation of [alpha]-Synuclein in Cerebellar Purkinje Cells of Diabetic Rats and Its Potential Relationship with Inflammation and Oxidative Stress Markers

Kakei, "Releasing dentate nucleus cells from Purkinje cell inhibition generates output from the cerebrocerebellum," PLoS ONE, vol.

Pathogenic Roles of Glutamic Acid Decarboxylase 65 Autoantibodies in Cerebellar Ataxias

Carlson, "Purkinje cell death after uptake of antiyo antibodies in cerebellar slice cultures," Journal of Neuropathology and Experimental Neurology, vol.

Anti-Yo Mediated Paraneoplastic Cerebellar Degeneration Associated with Pseudobulbar Affect in a Patient with Breast Cancer