rho·dop·sin

(rō-dŏp′sĭn)

Any of a class of reddish, light-sensitive pigments found in the retinal rods of the eyes of terrestrial and marine vertebrates, consisting of opsin and retinal. Also called visual purple.

[rhod(o)- + Greek opsis, sight; see -opsis + -in.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

rhodopsin

(rəʊˈdɒpsɪn)

(Biochemistry) a red pigment in the rods of the retina in vertebrates. It is dissociated by light into retinene, the light energy being converted into nerve signals, and is re-formed in the dark. Also called: visual purple See also iodopsin

[C20: from rhodo- + -opsis + -in]

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

rho•dop•sin

(roʊˈdɒp sɪn)

n.

a bright red photosensitive pigment found in the rod-shaped cells of the retina of certain fishes and most higher vertebrates: it is broken down by the action of dim light into retinal and opsin.

[1885–90; rhod- + Greek óps(is) sight, vision + -in¹]

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

rhodopsin - a red photopigment in the retinal rods of vertebrates; dissociates into retinene by light

retinal purple, visual purple

retinal rod, rod cell, rod - a visual receptor cell that is sensitive to dim light

opsin - retinal protein formed by the action of light on rhodopsin

retinal, retinene - either of two yellow to red retinal pigments formed from rhodopsin by the action of light

photopigment - a special pigment found in the rods and cones of the retina

Translations

rho·dop·sin

[MIM*180380]

n. rodopsina, pigmento de color rojo púrpura que se encuentra en los bastoncillos de la retina y que facilita la visión en luz tenue.

English-Spanish Medical Dictionary © Farlex 2012

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References in periodicals archive

The therapy aims to inhibit the formation of the mutated toxic version of the rhodopsin protein by specifically binding the mutated RHO mRNA.

ProQR Announces Clearance of IND to Start Clinical Trial of QR-1123 in Patients with Autosomal Dominant Retinitis Pigmentosa

A team of Brown University researchers found that opsin 3 -- a protein closely related to rhodopsin, the protein that enables low-light vision -- has a role in adjusting the amount of pigment produced in human skin, a determinant of skin color.

Adjusting Skin Color: Light-Sensitive Proteins

They demonstrated this through computer simulations and functional experiments on rhodopsin proteins regenerated in the lab.

New fish species discovered that can detect wavelengths

To assess differentiation efficiency of photoreceptor subtypes in retinal organoids older than W21, we measured opsins (rhodopsin, L/M opsin, and S opsin) positive area and total presumptive outer nuclear layer (ONL) area per retinal organoid (n = 14) with ImageJ software, according to a method published [14].

Generation of Retinal Organoids with Mature Rods and Cones from Urine-Derived Human Induced Pluripotent Stem Cells

Hirayama, "Stimulatory effect of cyanidin 3glycosides on the regeneration of rhodopsin," Journal of Agricultural and Food Chemistry, vol.

Cyanidin-3-glucoside Alleviates 4-Hydroxyhexenal-Induced NLRP3 Inflammasome Activation via JNK-c-Jun/AP-1 Pathway in Human Retinal Pigment Epithelial Cells

Transgenic mice with the rhodopsin promoter controlling human VEGF165 levels in photoreceptors (rho/VEGF mice) produce new vessels from the retina's deep capillary bed, starting at P10, which grow into the subretinal space [25, 40].

Flt3 Regulation in the Mononuclear Phagocyte System Promotes Ocular Neovascularization

Ablation of the mutant allele using CRISPR/Cas9 technology is another strategy that has been used in dominant forms for RP due to mutations in the gene encoding Rhodopsin (RHO).

Guiding Lights in Genome Editing for Inherited Retinal Disorders: Implications for Gene and Cell Therapy

Long-term rescue of retinal structure and function by rhodopsin RNA replacement with a single adeno-associated viral vector in P23H RHO transgenic mice.

Recent Advancements in Gene Therapy for Hereditary Retinal Dystrophies

A member of the UV7 opsin clade that is expressed in photoreceptors of the Aedes mosquito, AaRh10, was able to elicit a photoresponse when expressed in transgenic Drosophila (Hu et al., 2014); however, these responses were smaller and slower than expected for a visual rhodopsin. This result might only reflect poor compatibility between AaRh10 and the Drosophila photoreceptor environment.

Opsins and Their Expression Patterns in the Xiphosuran Limulus polyphemus

It is caused because rhodopsin, a light-sensitive protein found in the rod cells of the retina, regenerates more slowly as we age.

Improve night vision

However, in this present work, WFC, being directly associated to consciousness, is investigated in the retinal structure of 'rhodopsin' in vitro.

Wave function collapse in retinal structure under aided/un-aided conditions