mi·cro·sat·el·lite

(mī′krō-săt′l-īt′)

1. A short sequence of DNA consisting of multiple repetitions of a set of two to nine base pairs, used as a genetic marker when individuals differ in the number of repetitions.

2. A small artificial satellite, usually with a mass of less than 100 kilograms (220 pounds) when deployed in orbit.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

microsatellite

(ˌmaɪkrəʊˈsætəˌlaɪt)

(Genetics) genetics a section of DNA consisting of very short nucleotide sequences repeated many times, the number of repeats varying between members of the species: used as a marker in determining genetic diversity, identifying important genetic traits, and in forensics, population studies, and paternity studies

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

References in periodicals archive

High-resolution capillary array electrophoretic sizing of multiplexed short tandem repeat loci using energy-transfer fluorescent primers.

Genotyping energy-transfer-cassette-labeled short-tandem-repeat amplicons with capillary array electrophoresis microchannel plates

CODIS and PCR-based short tandem repeat loci: Law enforcement tools.

Anomalous amplification of the Amelogenin locus typed by AmpFLSTR[R] Profiler Plus[TM] amplification kit

In addition, fluorescent PCR by the use of polymorphic short tandem repeats (STRs) has recently been applied to the rapid detection of trisomies (7-10).

Diagnosis of trisomy 21 in fetal nucleated erythrocytes from maternal blood by use of short tandem repeat sequences

Validation of Polymerase Chain Reaction Analysis of Short Tandem Repeat Loci for Casework within the Oregon State Police Forensic Laboratory.

Modification of the stutter position label-filtering macro in the PE Biosystems Genotyper[R] Version 2.5 software package: resolution of stutter-filter back talk

[4] Nonstandard abbreviations: CMT, Charcot-Marie-Tooth; PMP22, peripheral myelin protein 22; RFLP, restriction fragment length polymorphism; STR, short tandem repeat; BAC, bacterial artificial chromosome; and HNPP, hereditary neuropathy with liability to pressure palsies.

Polymorphic short tandem repeats for diagnosis of the Charcot-Marie-Tooth IA duplication

PCR-based methods using short tandem repeats (STRs) (3, 15, 16), quantification of gene dosage (17,18), and detection of the unique junction fragment of the CMT1A/HNPP recombination (19) have also been reported.

New polymorphic short tandem repeats for PCR-based Charcot-Marie-Tooth disease type 1A duplication diagnosis

Some of the current clinical applications of MS are (a) DNA sequencing (8); (b) detection of genetic variations such as single-nucleotide polymorphisms (9), microsatellites (10), short tandem repeats (11), and small insertions/ deletions; and (c) gene expression.

Mass spectrometry of nucleic acids

Allele frequency distributions at several variable number of tandem repeat (VNTR) and short tandem repeat (STR) loci in a restricted Caucasian population from South Italy and their evaluation for paternity and forensic use.

Efficiency of two different nine-loci short tandem repeat systems for DNA typing purposes

Rapid diagnosis of aneuploidy in chromosomes 13, 18, 21, X and Y by quantitative fluorescence-PCR combined with short tandem repeat and fluorescence-labeled homologous gene quantitativePCR using 4-color fluorescently labeled universal primers.

Segmental Duplications as a Complement Strategy to Short Tandem Repeats in the Prenatal Diagnosis of Down Syndrome

Use of a novel panel of nine short tandem repeats for exact and high-resolution fingerprinting of Aspergillus fumigatus isolates.

In Vivo Selection of a Unique Tandem Repeat Mediated Azole Resistance Mechanism ([TR.sub.120]) in Aspergillus fumigatus cyp51A, Denmark

Evaluation of 13 short tandem repeat loci for use in personal identification applications.

Pattern Analysis of Short Tandem Repeats Allele Frequencies among the Population of Khuzestan Province, South of Iran

In conjunction, IntegenX solutions' RapidHIT platforms, software analysis tools and related consumables are highly compatible with Thermo Fisher's short tandem repeat (STR) chemistries for human identification.

Thermo Fisher Scientific buys IntegenX for undisclosed value