softening of the brain

(Pathology) an abnormal softening of the tissues of the cerebrum characterized by various degrees of mental impairment

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

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softening

References in classic literature

HAVING been summoned to serve as a juror, a Prominent Citizen sent a physician's certificate stating that he was afflicted with softening of the brain.

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When I returned alone to the picture-gallery--when I remembered that I had not even had the wit to improve my opportunity by discovering her name and address--I did really and seriously ask myself if these were the first symptoms of softening of the brain. I got up, and sat down again.

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"I say, Watson," he whispered, "would you be afraid to sleep in the same room with a lunatic, a man with softening of the brain, an idiot whose mind has lost its grip?"

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