An antiviral drug, C9H14N5O4P, used in the form of a prodrug (tenofovir disoproxil fumarate) to treat chronic hepatitis B and, in combination with other drugs, to treat HIV infection or to reduce the risk of HIV infection.
[teno-, of unknown origin + fo- (alteration of pho(spho)-) + (anti)vir(al).]
THURSDAY, July 25, 2019 (HealthDay News) -- Tenofovir preexposure prophylaxis (PrEP) therapy does not appear to be associated with clinically significant declines in bone mineral density (BMD) in the short term, according to a study published online June 19 in AIDS Research and Human Retroviruses.
Spring Bank also announces the expansion of a collaborative study in patients infected with chronic HBV involving the evaluation of multiple doses of inarigivir co-administered with tenofovir alafenamide 25mg to include the 400mg dose of inarigivir.
Tenofovir disoproxil fumarate (TDF) is a prodrug of tenofovir diphosphate, a structural analog of deoxyadenosine triphosphate, which is the natural substrate for the viral enzyme reverse transcriptase.
Biopharmaceutical company Gilead Sciences Inc reported on Monday the availability of Vemlidy (tenofovir alafenamide, TAF) in 25 mg for the once-daily treatment of adults with chronic hepatitis B with compensated liver disease upon approval from Taiwan National Health Insurance Administration of the Ministry of Health and Welfare.
Patients between 18 and 70 years receiving oral antiviral agents (lamivudine, entecavir, or tenofovir disproxil fumarate) for a minimum duration of 3 years due to CHB were included.
The patent and licensing status of entecavir and tenofovir, two WHO-recommended medicines for HBV treatment, were examined using the Medicines Patent Pool MedsPaL ([dagger]) database.
This study sought to assess the comparative immune reconstitution potential between tenofovir and zidovudine-based HAART regimens, which includes lamivudine and efavirenz in combination therapy It also aimed to investigate the adverse drug reactions/events (ADREs) associated with pharmacotherapy with these agents in a total of 106 HAART naive HIV patients.
Background: Tenofovir disoproxil (TDF) is a promising salvage therapy for patients with chronic hepatitis B (CHB) who failed regimens of other nucleoside analogues (NAs).
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.