levetiracetam, tiagabine, topiramate) and the antipsychotic olanzapine show some promise as acute treatments, but adequate randomised controlled trials (RCTs) are lacking.
(21) Vigabatrin and tiagabine two drugs that act on different aspects of GABAergic neurotransmission, have been studied in an animal model of noise-induced tinnitus.
Other potential anticonvulsant agents include gabapentin, topiramate, pregabalin and tiagabine, which have limited protein binding and, theoretically, no effects on the cytochrome P-450 system.
15 October 2010 - US-based biopharmaceutical company Cephalon Inc (NASDAQ: CEPH) today announced that a Risk Evaluation and Mitigation Strategy (REMS) for its antiepileptic medication GABITRIL (tiagabine hydrochloride) has been approved by the US Food and Drug Administration (FDA).
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