Yamabe et al., "Mutation and haplotype analyses of the
Werner's syndrome gene based on its genomic structure: Genetic epidemiology in the Japanese population," Human Genetics, vol.
Differential diagnoses are other ageing syndromes like
Werner's syndrome (adult progeria), Cockyane's syndrome, Acrogeria, and Rothmund-Thomson syndrome which can be differentiated by their clinical features.
They includes "Dreaming Water," the life of a woman suffering from
Werner's syndrome, which ages a person twice as fast as normal; and the inhabitants of a leper colony in "The Samurai's Garden."
INTRODUCTION:
Werner's syndrome is a progeroid syndrome.
Werner's syndrome is a rare inherited disorder characterized by short stature, sclerosed skin, cataract and premature aging of the face.
Unlike most other "accelerated aging diseases" (such as
Werner's syndrome, Cockayne's syndrome, or xeroderma pigmentosum), progeria is not caused by defective DNA repair.
Researchers at the Centre de Recherche en Cancerologie in Quebec said vitamin C reversed accelerated aging in a mouse model of
Werner's syndrome.
Mutation in the gene WRN is responsible for
Werner's Syndrome, which causes people to age rapidly.
Investigators have found that people who have
Werner's syndrome (WS), a rare disease with several features of premature aging, have a defect in one of their helicases.
Cate is caring for her 34-year-old daughter Hana, who is suffering from
Werner's syndrome, a disease in which the person ages prematurely.
The baby could develop
Werner's Syndrome, which leads to massive ageing and can kill before victims before they are 50.