X-linked gene

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Noun1.X-linked gene - a gene located on an X chromosome
cistron, gene, factor - (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"
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The X chromosome contains a lot more genes than Y chromosome, so if a boy, for example, inherits an X-linked gene defective from his mother, and his gene is responsible for neuro development he might have mental retardation.
The mutations in X-linked gene, filamin A ( FLNA ) gene, were identified in approximately 100% of familial PNHs and 25% of sporadic cases.[sup][2],[3] Here, we reported a novel frameshift mutation of FLNA gene in a Chinese family with PNH.
The cause of Rett Syndrome's terrible constellation of symptoms lies in mutations of an X-linked gene called MECP2 (methyl CpG-binding protein).
These cell-based models require that only the diseased copy of an X-linked gene be expressed, with the normal copy of the gene in females silenced via XC1.
This paralogous relationship might be helpful in exploring more autosomal genes by using X-linked gene data.
Because girls have two X chromosomes, and therefore two copies of every X-linked gene, they are less likely than boys to have symptoms from X-linked genetic diseases because boys don't have a backup copy if an X-chromosome gene has a mutation.
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