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The company added the stand-alone trial is designed to evaluate the efficacy, safety and pharmacokinetics of ivosidenib in Chinese patients with IDH1 mutant R/R AML the most common type of acute leukemia in adults and is characterised by rapid disease progression.

CStone to begin ivosidenib Phase I bridging registrational study in China in IDH1 mutant relapsed or refractory AML patients

We chose 12 to 24 months prior to implementation for comparison because in the year immediately prior to implementation of PDAT with IR, we had initiated IR for acute leukemia and had started to direct clinician test ordering in an informal manner using email and phone calls.

Combined Pathology-Driven Algorithmic Testing and Integrated Reporting for Bone Marrow Examination

For more than 20 years, the FAB classification for acute leukemia has been the major system of classification.

Immunophenotypic characterisation of morphologically diagnosed cases of Acute Myeloid Leukaemia (AML)

The Phase 2 clinical trial was evaluating VL-2397 as a potential first-line treatment for invasive aspergillosis in immunocompromised adults with acute leukemia or recipients of an allogeneic hematopoietic cell transplant.

Vical to discontinue development of VL-2397, to consider strategic options

About seventy-five percent of all acute leukemia seen in the pediatric population are known as "ALL" or acute lymphocytic (or lymphoblastic) leukemia.

Pediatric Leukemia

A 20-minute test confirmed he had acute leukemia and led to his admission at Kenyatta National Hospital.

Journalist Dennis Omondi dies from cancer for lack of bone marrow donor

Material and Methods: All peripheral blood and bone marrow samples to confirm the suspicion of acute leukemia with flow cytometric immunephenoltyping were included in the study.

SPECTRUM OF ACUTE LEUKEMIAS AND ABERRANT MARKERS EXPRESSION BASED ON FLOWCYTOMETRY IN A TERTIARY CARE CENTRE

Unmanipulated haploidentical-related donor (HRD) HCT has yielded encouraging outcomes in the treatment of hematologic malignancies, making it an alternative option for patients who do not have an HLA-matched sibling donor (MSD).[36],[37],[38],[39],[40] One study even reported that unmanipulated HRD-HCT from granulocyte colony-stimulating factor (G-CSF)-mobilized bone marrow and peripheral blood stem cells (PBSCs) achieved a stronger graft-versus-leukemia (GVL) effect than MSD-HCT in patients with high-risk acute leukemia.[36] Moreover, PBSC transplantation is less invasive for the donor and easy to perform.

Efficacy and Safety of Unmanipulated Haploidentical Related Donor Allogeneic Peripheral Blood Stem Cell Transplantation in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Out of these, 23 cases (58.97%) were of acute leukemia including both acute myeloid and acute lymphocytic leukemia; nine cases (23.07%) were of acute leukemia while eight cases (20.15%) of acute myeloid and 06 cases (15.38%) of acute lymphoblastic leukemia.

MALIGNANT HEMATOLOGICAL DISORDERS ON BONE MARROW ASPIRATION : AN EXPERIENCE FROM TERTIARY CARE HOSPITALS

Vical plans to initiate a single Phase II trial for the treatment of invasive aspergillosis (IA) in acute leukemia patients and allogeneic hematopoietic cell transplant (HCT) recipients in the fourth quarter of 2017.

Vical Inc. was advised by the FDA that its investigational antifungal VL 2397 would be eligible for a Limited Use Indication (LUI) approval assuming a successful outcome of a single Phase II trial conducted in accordance with a protocol and statistical analysis plan consistent with the Agency's advice

Acute leukemia in pregnancy with ovarian metastasis: A case report and review of the literature.

A rare case of massive hepatosplenomegaly due to acute lymphoblastic leukaemia in pregnancy