In the adrenally sufficient individual, the thyrotoxic state both increases the production of cortisol, and shortens the half-life of cortisol due to an increased turnover rate, with a net effect of normal circulating cortisol levels [3].
The aromatase inhibitors (AIs) are a class of agents that block conversion of adrenally produced precursor compounds to estrogenic molecules, particularly estradiol and estrone, in peripheral tissues and within breast cancers themselves.
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.