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In fact, HS in children may be a marker of precocious puberty, as noted in those presenting with adrenal hyperplasia and premature adrenarche.

Low incidence of HS in children does not diminish importance of early diagnosis

Persistence of delayed adrenarche in boys with thalassaemia.

BODY MASS INDEX IN THALASSEMIA CHILDREN

The Pit-1 gene is also responsible for the development of the anterior pituitary [4], inducing the differentiation of hepatic progenitor cells into PRL-producing ones [5] and delaying adrenarche in humans [6].

Association of polymorphisms in Pit-1 gene with growth and feed efficiency in meat-type chickens

The absence of 17,20 lyase activity in the adrenal gland also results in deficiency of DHEA sulfate (DHEA-S), causing failure of adrenarche and pubic and axillary hair development (5,6).

A Rare Cause of Congenital Adrenal Hyperplasia: Clinical and Genetic Findings and Follow-up Characteristics of Six Patients with 17-Hydroxylase Deficiency Including Two Novel Mutations

Circulating plasma leptin and IGF-1 levels in girls with premature adrenarche: Potential implications of a preliminary study.

Childhood Obesity and Accelerated Timing of Dental Development A Critical Review

The levels of 17a-hydroxyprogesterone and pregnenolone in the healthy boys did not vary significantly among the different adrenarche ages, from approximately 6-8 years old (before puberty initiation) to 9 years old.

Liquid Chromatography-Tandem Mass Spectrometry-Based Characterization of Steroid Hormone Profiles in Healthy 6 to 14-Year-Old Male Children

(2) Women are at especially high risk if they have a history of oligoovulatory infertility; obesity and/or insulin resistance; diabetes type 1, 2, or gestational; premature adrenarche (stage of puberty when the adrenal cortex begins to secrete androgens, typically signified by pubic and axillary hair growth); any first-degree relatives with PCOS; or use of antiepileptic drugs.

PCOS Variants in the Management of Infertility: Low-Androgen, Lean-Type and Post-Contraceptive Amenorrhea

Miller, "Serine phosphorylation of human P450c17 increases 17,20-lyase activity: implications for adrenarche and the polycystic ovary syndrome," Proceedings of the National Academy of Sciences of the United States of America, vol.

Role of Lipotoxicity and Contribution of the Renin-Angiotensin System in the Development of Polycystic Ovary Syndrome

2014), but was inversely associated with odds of having reached adrenarche or pubarche in boys (n =107) (Ferguson et al.

First-trimester urinary bisphenol a concentration in relation to anogenital distance, an androgen-sensitive measure of reproductive development, in infant girls

A diagnosis not to be missed: Non-classic steroid 11E-hydroxylase deficiency presenting with premature adrenarche and hirsutism.

Hiperplasia suprarrenal congenita por deficit de 11-beta-hidroxilasa: descripcion de una nueva mutacion, R384X

Androgen synthesis in adrenarche. Reviews in Endocrine & Metabolic Disorders, vol.

Adrenal glands of Spix's yellow-toothed cavy (Galea spixii, Wagler, 1831): morphological and morphometric aspects/ Glandulas adrenais de preas (Galea spixii, Wagler, 1831): aspectos morfologicos e morfometricos