chemical science, chemistry - the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions
change state, turn - undergo a transformation or a change of position or action; "We turned from Socialism to Capitalism"; "The people turned against the President when he stole the election"
The plasma sample (250[micro]l) was mixed with 14.1 of internal standard solution (diazepam) before the addition of 200 [micro]l of buffer bicarbonate (pH 10) to alkalify the plasma drug and then 1.5 ml of dichloromethane and 3.5 ml of hexane were mixed and shaken for 5 min.
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alkalify - turn basic and less acidic; "the solution alkalized"