allopurinol

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al·lo·pu·ri·nol

 (ăl′ō-pyo͝or′ə-nôl′, -nōl′, -nŏl′)
n.
A drug, C5H4N4O, that inhibits uric acid formation in the body and is used to treat conditions, especially gout, that cause elevated uric acid levels.
[allo- + purin(e) + -ol.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

allopurinol

(ˌæləʊˈpjʊərɪˌnɒl)
n
(Pharmacology) a synthetic drug that reduces blood concentrations of uric acid and is administered orally in the treatment of gout. Formula: C5H4N4O
[C20: from allo- + purine + -ol1]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.allopurinol - a drug (trade name Zyloprim) used to treat gout and other conditions in which there is an excessive buildup of uric acidallopurinol - a drug (trade name Zyloprim) used to treat gout and other conditions in which there is an excessive buildup of uric acid
Zyloprim
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

allopurinol

n alopurinol m
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
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References in periodicals archive
The XOI allopurinol (Zyloprim[R]) has been the first-line treatment for gout for decades.
What to Expect from Your Gout Treatment: Follow your doctor's prescription to lower your uric acid levels and your long-term risk of painful flare-ups
Terrence Gibson remarked that Allopurinol remains the first choice for serum uric acid (SUA).
DMARDs should be started within three months of diagnosis of Rheumatoid Arthritis-John Axford
First approved by the United States Food and Drug Administration (FDA) in 1966, the xanthine oxidase inhibitor allopurinol remains a cornerstone of urate-lowering therapy (ULT) for chronic gout management.
Low-Dose Allopurinol Promotes Greater Serum Urate Lowering in Gout Patients with Chronic Kidney Disease Compared with Normal Kidney Function
The gout drug febuxostat (Uloric) poses a significantly higher risk of all-cause and heart-related death than does the popular alternative drug allopurinol, the Food and Drug Administration declared on Feb.
Death data spur black-box warning for gout drug Uloric
Objective: To determine the efficacy of high-dose allopurinol in reducing left ventricular mass in patients with left ventricular hypertrophy by comparing its efficacy with febuxostat.
Efficacy of high dose Allopurinol in reducing left ventricular mass in patients with left ventricular hypertrophy by comparing its efficacy with Febuxostat - a randomized controlled trial
20, 2018 (HealthDay News) -- Allopurinol dose escalation is not associated with reductions in mortality risk among patients with gout, according to a study published in the August issue of Arthritis & Rheumatology.
Allopurinol Dose Escalation for Gout Doesn't Improve Mortality; Linked to small increase in mortality; at 2 years, 31 percent of dose escalators achieved serum urate goal
Miscellaneous drugs such as anticonvulsants, sulphonamids, dapson, allopurinol, minocycline, fluoroquinolone, and gold salts may cause this reaction.
Effects of IVIG and Pulse Steroid Therapy in a Case of Allopurinol Induced DRESS Syndrome
Available US Food and Drug Administration (FDA)-approved options for lowering sUA include xanthine oxidase inhibitors (allopurinol and febuxostat) that prevent production of uric acid; a uricosuric agent (probenecid) that increases uric acid output in urine; and a uric acid-specific enzyme (pegloticase) that converts uric acid to allantoin.
Long-term Treatment of Gout: New Opportunities for Improved Outcomes
Orpiada was prescribed allopurinol, a common medication for treatment of high uric acid.
Dubai woman saved from deadly skin disorder
ORLANDO--Long-term treatment with febuxostat in gout patients with comorbid cardiovascular disease conferred significantly higher risks of both cardiovascular death and all-cause mortality compared with allopurinol, in the Food and Drug Administration--mandated postmarketing CARES trial, William B.
Febuxostat increased cardiovascular mortality in CARES trial
Allopurinol is a xanthine oxidase inhibitor and is used in the treatment of gout.
Hyperuricemia Induces Wnt5a/Ror2 Gene Expression, Epithelial--Mesenchymal Transition, and Kidney Tubular Injury in Mice
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