an·eu·ploid

(ăn′yə-ploid′)

adj.

Having a chromosome number that is not a multiple of the haploid number for the species.

A cell or an organism characterized by an aneuploid chromosome number.

an′eu·ploi′dy (-ploi′dē) n.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

aneuploidy - an abnormality involving a chromosome number that is not an exact multiple of the haploid number (one chromosome set is incomplete)

abnormalcy, abnormality - an abnormal physical condition resulting from defective genes or developmental deficiencies

Translations

trisomía

aneuploïdie

Mentioned in

References in periodicals archive

Study of aneuploidy and DNA fragmentation in gametes of patients with severe teratozoospermia.

Association of Sperm Aneuploidy Frequency and DNA Fragmentation Index in Infertile Men

* Qualitative fluorescence PCR (QF-PCR): Detection of aneuploidy (such as Down syndrome) and repeat expansion diseases (such as Fragile X and Huntington's disease).

PCR: a versatile tool--from detecting genetic diseases and cancers to monitoring stability after bone marrow transplants

All pregnant women considered to have increased risk factors or, less commonly, to be anxious about pregnancy should be offered a prenatal diagnostic test for the confirmation of fetal chromosome aneuploidy. (1) The most common numerical variations of chromosomes recognized in prenatal samples are 13, 18, or 21 trisomies and sex chromosome aneuploidies, representing approximately 70% of all chromosomal anomalies detected.

Segmental Duplications as a Complement Strategy to Short Tandem Repeats in the Prenatal Diagnosis of Down Syndrome

Prequel Prenatal Screen with expanded aneuploidy analysis can potentially improve birth outcomes by identifying more pregnancies at risk for birth defects and syndromes, as well as those at risk for pregnancy complications due to these chromosome changes in the placenta.

Myriad Genetics subsidiary enhances Prequel Prenatal Screen

Spectrum[R] preimplantation genetic screening for aneuploidy (PGT-A) from Natera, Inc, has demonstrated that it improves in vitro fertilization (IVF) results for all women, including those of advanced maternal age, announces Natera.

PREIMPLANTATION GENETIC TESTING

Detection rates for aneuploidy by first-trimester and sequential screening.

Triploidy and Routine Combined First Trimester Pregnancy Screening

DNA repair errors are responsible for a variety of birth defects as well as conditions like Down syndrome or Turner syndrome that result from an incorrect number of chromosomes in an individual, also called aneuploidy.

OMRF receives $1.4M for study

The researchers note that the clinical adoption of cfDNA sequencing for chromosomal aneuploidy screening has already had a global effect.

Review Addresses Cell-Free DNA Sequencing in Pregnancy; cfDNA testing for trisomy 21, 18, 13 recommended in pregnancy; no FDA oversight for testing

He said, "a few recent studies have shown that embryo aneuploidy (chromosome abnormality preventing embryo implantation or causing miscarriage) changes with age in a u-shaped curvilinear regression, declining steadily before age 30 and increasing steadily thereafter.

Assisted Reproductive Technology / In Vitro Fertilization (ART / IVF) Success is Lower in Young Women; Its Decline Begins Earlier Than Thought, Occurs at Increasing Rates

However, rapid aneuploidy testing methods such as fluorescent in situ hybridization (FISH), quantitative fluorescence-polymerase chain reaction (QF-PCR), and multiplex probe ligation assay (MLPA) are also routinely used for prenatal diagnosis in the laboratory (4).

Segmental duplication-quantitative fluorescent-polymerase chain reaction: An approach for the diagnosis of Down syndrome in India/Segmental duplikasyon-kantitatif floresan polimeraz zincir reaksiyonu: Hindistan'da Down sendromu tanisina yonelik bir yaklasim

Although not yet approved by the FDA, prenatal genomic screening for aneuploidy has been extensively validated worldwide.

Unusual Prenatal Genomic Results Provide Proof-of-Principle of the Liquid Biopsy for Cancer Screening