Evans syndrome is an uncommon condition characterised by Immune thrombocytopenia (ITP) and Autoimmune haemolytic anaemia (AIHA) that can coexist or one follows the other, and it is diagnosed with a positive Direct
antiglobulin test (DAT).
The trial has also enrolled 11 patients with wAIHA, 8 of which were Direct
Antiglobulin Test C3+; 5 of the C3+ wAIHA patients have been on APL-2 for at least 168 days.
Rose Bengal testi, serum aglutinasyon testi (SAT),
antiglobulin veya Coombs testi, mikroaglutinasyon testi (MAT), Brucellacapt, enzim ile immunosorbent testi (ELISA) ve Dolayli floresan antikor testi (IFA) gibi testler kullanilmaktadir.
All 'D' negative samples by tube method were confirmed for weak D by an indirect
antiglobulin test and subsequently by column agglutination technology.
The direct
antiglobulin test (DAT) is positive in acquired immunemediated spherocytosis, unlike a negative result seen in hereditary spherocytosis.
The direct
antiglobulin test result is negative in many cases, and new alloantibodies may or may not be present.
Bio-Rad provides a wide variety of platforms, reagents, data management, and connectivity solutions to address different blood typing needs, offering efficient and reliable results for blood grouping, phenotyping, crossmatching, antibody screening and identification, direct
antiglobulin tests, and single antigen typing.
Direct
antiglobulin test (DAT) was also performed for each sample.
Hemolytic anemia and positive
antiglobulin test has been described during Rifampicin treatment [5].
Initial investigations showed positive direct
antiglobulin test (DAT) indicating autoimmune haemolytic anaemia with haemoglobin (Hb) of 50g/L.
He underwent fludarabine-cyclophosphamide-antithymocyte
antiglobulin preparation prior to a single cord blood allogeneic transplant.