[USPRwire, Wed Jul 17 2019] Thrombosis drugs help in the prevention or inhibition of thrombus, by mimicking the role of
antithrombin, a protein molecule produced in the body, which helps clotting of the blood.
Normal distribution of quantitative variables (protein C, protein S,
antithrombin III, DD, FDPs, CRP, hs-CRP, WBC count, procalcitonin) was evaluated using Kolmogorov-Smirnow Z (K - S) test.
Two concurrent chromosomal aberrations involving interstitial deletion in 1q24.2q25.2 and inverted duplication and deletion in 10q26 in a patient with stroke associated with
antithrombin defciency and a patent foramen ovale.
Inherited
antithrombin deficiency Type IIb alters what and results in what?
They express
antithrombin resistance conferring a major susceptibility to thrombosis ([4,5]).
Acutely ill patients may have an
antithrombin deficiency, resulting in an inaccurately low aPTT and undue coagulation (Zehnder, Price, & Jin, 2012).
Application of
Antithrombin III Is the Best Anticoagulation Strategy for Splenectomy.
In a cohort study containing three cohorts of families with a hereditary deficiencies of protein C, protein S, and
antithrombin III, compared with nondeficient family members, subjects with protein S or protein C deficiency but not
antithrombin III deficiency had a higher risk for arterial thromboembolism before 55 years of age that was independent of their history of prior venous thromboembolism [4].
pseudomallei infection, leading to depletion of the natural endothelial modulators protein C, protein S, and
antithrombin [10,11].
Antithrombin is a natural anticoagulant that inhibits thrombin (factor IIa), factor Xa, and other serine proteases in the coagulation cascade.