(39) This was a huge controversy and not only of academic interest but also, because of prior success making antityphoid fever vaccines, bacteriologists were attempting to determine what organism or combination of organisms should be used to make a protective influenza vaccine.
Due to emerging and spreading of multidrug resistance against the conventional antityphoid drugs (chloramphenicol, co-trimoxazole, and ampicillin) among salmonella isolates, Flouroquinolones became a choose of major antimicrobial agent [3] These are the most effective agents with high cure rate and low relaps and fecal carriage rates.
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