ap·op·to·sis

(ăp′əp-tō′sĭs, ăp′ə-tō′-)

A natural process of self-destruction by degradative enzymes in certain cells, such as epithelial cells and erythrocytes, that are genetically programmed to have a limited lifespan or are damaged, as by irradiation or toxic drugs. Also called programmed cell death.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

apoptosis

(ˌæpəpˈtəʊsɪs)

(Biology) biology the programmed death of some of an organism's cells as part of its natural growth and development. Also called: programmed cell death

[C20: from Greek: a falling away, from apo- + ptōsis a falling]

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

apoptosis - a type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival

caspase-mediated cell death, programmed cell death

cell death, necrobiosis - (physiology) the normal degeneration and death of living cells (as in various epithelial cells)

Translations

Apoptose

apoptosis

apoptose

Mentioned in

References in periodicals archive

Ovarian follicular atresia and postovulatory regression in mammals is mediated by apoptosis, which is a natural occurring cause of cellular death.

Atresia and Apoptosis in Pre- and Postovulatory Follicles of Sharptooth Catfish (Clarias gariepinus, Burchell, 1822)

Cell Death: Apoptosis and Other Means to an End, 2nd Edition

Background: Oxidized low-density lipoprotein (ox-LDL)-induced oxidative stress and endothelial apoptosis are essential for atherosclerosis.

Inhibitory Effects of Simvastatin on Oxidized Low-Density Lipoprotein-Induced Endoplasmic Reticulum Stress and Apoptosis in Vascular Endothelial Cells

A recent study confirmed the role of PC that could induce apoptosis in adipocyte cell culture (11), so PC alone might be developed into a safer lipolytic agent that causes less necrosis, and thus less inflammation and side effects.

Apoptosis of Adipose-Derived Stem Cells Induced by Liposomal Soybean Phosphatidylcholine Extract

Objective: To examine the HCV genotype 3a specific effects on caspases involved in apoptosis, expression levels of caspases-3, 8, 9, and 10 in peripheral blood mononuclear cells (PBMCs) of HCV genotype 3a infected patients.

TRANSCRIPTOME ANALYSIS OF APOPTOTIC MARKERS IN PERIPHERAL BLOOD MONONUCLEAR CELLS OF HCV GENOTYPE-3A INFECTED PATIENTS

The initiation of cell cycle arrest, apoptosis and autophagy are the important strategies in cancer treatment as well as prevention.

2-Methyl 2-butanol suppresses human retinoblastoma cells through cell cycle arrest and autophagy

Flow cytometry was used to identify the amount of apoptosis. SPSS 15 was used to analyse the data.

Clinical characterisation and cytological study of dry eye in patients with autoimmune disease

Previous studies have shown that [beta] cell apoptosis and dysfunction are significantly increased in patients and animals with type 2 diabetes [1-3].

TERT and Akt Are Involved in the Par-4-Dependent Apoptosis of Islet [beta] Cells in Type 2 Diabetes

This review will summarize recent evidences in the field of STING-mediated cell death (including apoptosis and necrosis) and discuss relevant clinical significance.

STING Signaling Promotes Apoptosis, Necrosis, and Cell Death: An Overview and Update

In addition, whether miR-378 regulates the apoptosis of bovine granulosa cells (bGCs) remains undetermined.

Short Communication - MIR-378 INDUCES APOPTSIS OF GRANULOSA CELLS DURING FOLLICLE DEVELOPMENT IN CATTLE

Currently most anti-cancer therapies (chemotherapy, radiation and immunotherapy) work by killing cancer cells through a process called apoptosis, which activates proteins called caspases, leading to cell death.

Hope for new process to eradicate cancer cells