ar·se·nic trioxide

(är′sə-nĭk)

A poisonous, white amorphous powder, As₂O₃, used in insecticides, rat poisons, weed killers, pigments, and preservatives for hides and wood.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

arsenic trioxide

(Elements & Compounds) a white poisonous powder used in the manufacture of glass and as an insecticide, rat poison, and weedkiller. Formula: As2O3. Also called: arsenic

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ar′senic triox′ide

a white, tasteless, poisonous powder, As₂O₃, used chiefly in the manufacture of pigments and glass and as an insecticide or weed-killer.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

arsenic trioxide - a white powdered poisonous trioxide of arsenic; used in manufacturing glass and as a pesticide (rat poison) and weed killer

arsenic, arsenous anhydride, arsenous oxide, ratsbane, white arsenic

trioxide - an oxide containing three atoms of oxygen in the molecule

Mentioned in

References in periodicals archive

The European Commission designated the medicinal product arsenic trioxide an orphan drug in October 2000.

Cell Therapeutics TRISENOX granted European authorization

The findings from the phone survey included use of arsenic, arsenic trioxide, asbestos, benzene, lead chromate, sodium arsenate, and sodium dichromate in pure form for science or chemistry experiments or demonstrations.

Reducing carcinogens in public schools: a non-regulatory approach by a regulatory agency

Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells.

E2F1-mediated FOS induction in arsenic trioxide-induced cellular transformation: effects of global H3K9 hypoacetylation and promoter-specific hyperacetylation in vitro

Arsenic trioxide in hematological malignancies: the new discovery of an ancient drug.

Effects of arsenic on osteoblast differentiation in vitro and on bone mineral density and microstructure in rats

Clinical studies consistently demonstrate that arsenic trioxide, used to treat acute promyelocytic leukemia, induces QT prolongation, torsades de pointes (a life-threatening polymorphic ventricular tachycardia), and sudden death (Ohnishi et al.

Arsenic exposure from drinking water and QT-interval prolongation: results from the health effects of Arsenic Longitudinal Study

Most of the studies treated animals with AsIII or arsenic trioxide, but other arsenicals have also been studied (Aguilar et al.

Evaluation of the association between arsenic and diabetes: a National Toxicology Program workshop review

Other studies reported that oxidative DNA damage (urinary 8-hydroxy-2'-deoxyguanosine) was repaired and returned to normal in patients 180 days after accidental oral intake of arsenic trioxide (Mahata et al.

Arsenic reduction in drinking water and improvement in skin lesions: a follow-up study in Bangladesh

Myocardial toxicity of arsenic trioxide in a mouse model.

Arsenic toxicology: translating between experimental models and human pathology

(2006) demonstrated that arsenic trioxide induces apoptosis by up-regulation of phosphorylated H2AX and may be one of the mechanisms by which arsenic trioxide acts as an antineoplastic agent (Figure 2).

An emerging role for epigenetic dysregulation in arsenic toxicity and carcinogenesis

OBJECTIVE: We investigated the effects of arsenic trioxide [As.sub.2][O.sub.3] on the myogenic differentiation of myoblasts in vitro and muscle regeneration in vivo.

Arsenic inhibits myogenic differentiation and muscle regeneration