Fevipiprant, which is being developed by Novartis, reduced a
biological marker of asthma nearly five-fold in the 12-week trial involving 61 patients, researchers said on Saturday.
The research team, led by Dr James Brown, has proven a significant link exists between Irisin levels in the blood and a
biological marker of ageing called telomere length.
Higher levels of the chemicals were associated with higher levels of nitric oxide in exhaled breath, which is a
biological marker of airway inflammation.
Objective: The study was carried out to evaluate the role of serum eosinophil cationic protein (ECP) as a
biological marker for the diagnosis and to assess the severity of bronchial asthma.
Greater exposure to tobacco smoke was also associated with higher levels of a
biological marker for "bad" cholesterol, or low-density lipoprotein (LDL).
A chemist for the Hershey chocolate company tested the pottery and found traces of theobromine, a
bioLogicaL marker for cacao, from which chocolate is made.
"This abnormal or accelerated rate of head circumference growth is a
biological marker for autism.
By looking at the smooth muscle cells of diseased blood vessels, the experts were able to identify accelerated telomere damage - a
biological marker of DNA ageing.
Certainly, the current study will not immediately produce a
biological marker for clinicians.
Measurement of S-100B has been proposed as a
biological marker of brain damage, e.g., head injury, cerebral hypoxia, and stroke (2), and of malignant melanoma (3).