The following combined two groups of keywords were used: (lupus, systemic lupus erythematosus, SLE, lupus-like, SLE-like, drug induced lupus) and (carbamazepine, Tegretol, anticonvulsant).
In her detailed history, it was learned that the patient had used valproic acid in the last six months and carbamazepine was added to treatment one month ago because her seizures could not be controlled.
Thus, the present work aimed to develop and apply a method based on the solid-phase extraction of caffeine, atrazine, and carbamazepine followed by the quantification by ultra-efficiency liquid chromatography coupled to a high-resolution hybrid mass spectrometer (quadrupole-time-of-flight).
Each group comprised of 100 subjects labeled as Group-A (control group had healthy individuals), Group-B (newly diagnosed epileptic patients without antiepileptic therapy), Group-C (epileptic patients on Carbamazepine therapy, which was further subdivided into C-I having epileptic patients on Carbamazepine therapy less than 1 year n=33, C-II had epileptic patients on Carbamazepine therapy 1-2 years n = 33 and C-III comprised of epileptic patients on Carbamazepine therapy more than 2 years n = 34).
The research team discovered in lab and mouse studies that the drug carbamazepine, already approved for treating conditions such as epilepsy and bi-polar disease, can significantly reduce the effects of MCDS.
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.