n. carcinosarcoma, neoplasma maligno formado por células carcinogénicas y de sarcoma. Este tipo de neoplasma se observa en la tiroides, la garganta y los ovarios.
The patient was eventually diagnosed with a carcinosarcoma, which was classified as IVB (T3N2M0) per the 8th American Joint Committee on Cancer Tumor-Node-Metastasis staging system.
(1) It is characterized by the histologic combination of malignant teratoma and carcinosarcoma with a triphasic growth pattern including epithelial, mesenchymal and primitive neuroectodermal components (2), and it mainly occurs in the nasal cavity and paranasal sinuses, although tumours occurring at other locations like nasopharynx and oral cavity have also been described.
Cases of non-primary bladder cancer (direct extension of adenocarcinoma of the rectum in 1 patient), non-urothelial bladder cancers (carcinosarcoma in 1 patient and fibrosarcoma in 1 patient) and non-malignant bladder conditions (emphysematous cystitis in 1 patient and eosinophilic cystitis in 1 patient) were excluded.
Therefore, endometrial neoplasms involving giant cells were considered and differential diagnosis included carcinoma, carcinosarcoma, leiomyosarcoma with osteoclast-like giant cells, undifferentiated sarcoma and choriocarcinoma with osteoclast-like giant cells.
To the Editor: A uterine carcinosarcoma (malignant mixed Mullerian tumor [MMMT]) is a rare, aggressive, malignant tumor which demonstrates both malignant epithelial (carcinoma) and mesenchymal (sarcoma) components.[1] MMMTs account for 2-5% of all uterine malignancies.
According to World Health Organization histological classification (2005), 'malignant mixed tumors,' should be divided into three different clinical and histological entities: CaExPA, carcinosarcoma (true malignant mixed tumors), and metastasizing PA.
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