In addition, triple
chronotherapy (wake therapy + sleep phase advance + bright light therapy) provides a quick, effective non-drug treatment for even severe suicidal depressions.
Nowadays, Pulsatile[R] and Diffucap[R] systems are gaining much research interest in the
chronotherapy of circadian rhythm-based ailments so as to release the drug after a predetermined lag phase.
The high prevalence of multi-day seizure cycles could present an opportunity to improve treatment through development of patient-specific
chronotherapy or the riming of medication to match when seizures would be most likely.
Resistant hypertension and
chronotherapy. Mater Sociomed.
However, knowing the temporal variability (ultrafine, circadian, infradian, circaseptan, circatrigintan, and circannual) of the manifestations and the security of drug utilization constitutes the reason of a new approach of the therapy -
chronotherapy.
The therapeutic outcomes of diseases such as bipolar disorder, rheumatoid arthritis, hypertension, and cancer which follow the circadian rhythm have been optimized through
chronotherapy [4, 5].
With this, the connection between chronobiology and
chronotherapy can be more strongly established in the field of psychiatry.
As the concept of
chronotherapy is emerging (in which delivery of treatment is coordinated with circadian rhythm), timely administered prednisolone will have a more significant effects on early morning symptoms.
Another form of sleep deprivation called
chronotherapy, which combines forced wakefulness with bright light therapy, may stave off depressive symptoms longer, research suggests.
Findings from the MAPEC (Monitorizacion Ambulatoria para Prediccion de Eventos Cardiovasculares) study suggest that bedtime
chronotherapy with [greater than or equal to]1 conventional hypertension medication to target sleep blood pressure significantly reduces cardiovascular disease risk [13].
Shahiwala, "Statistical optimization of ranitidine HCl floating pulsatile delivery system for
chronotherapy of nocturnal acid breakthrough," European Journal of Pharmaceutical Sciences, vol.
The ABPM is a suitable method to clarify the diagnosis of hypertension in borderline cases and define the
chronotherapy in hypertensive patients.