In the digestive gland, most of Cd and Zn appear to be bound to other
cytosolic proteins than to MTs (Tanaka et al.
Among the topics are the nomenclature and molecular biology of the human sulfotransferase family, the pharmocogenetics and pharmacogenomics of sulfate conjugation, molecular cloning of the human
cytosolic sulfotransferases, sulfotransferases in the human fetus and neonate, estrogen sulfotransferase in breast cancer, species differences in
cytosolic sulfotransferases, and the activation and inactivation of carcinogens and mutagens by human sulfotransferases.
"Glucocorticoids are very lipophilic molecules and are able to penetrate the cell membrane and bind to the
cytosolic glucocorticoid receptor complex, which becomes activated and moves into the nucleus where it binds to specific DNA sites," he explained.
has patented a quantitative method for the molecular diagnosis of autosomal recessive spinal muscular atrophy (SMA) by measuring the amount of
cytosolic mRNA from human muscle cells.
The formation of plasma membrane blebs in hepatocytes exposed to agents that increase
cytosolic Ca2+ is mediated by the activation of a non-lysosomal proteolytic system.
Results: Exercise-induced increases in plasma markers of purine catabolism (hypoxanthine, xanthine oxidase and serum uric acid) and circulating
cytosolic proteins (myoglobin, fatty acid-binding protein, and creatine kinase) were significantly attenuated by LCLT.
A mechanism, which is consistently implicated in apoptosis, is the activation of a series of
cytosolic proteases, the caspases.
Importantly, adapalene does not bind to the
cytosolic retinoic acid binding protein, so that constant levels of the drug reach the target cell nucleus throughout treatment.
Conklin and Last (1995) monitored the accumulation of mRNAs encoding both
cytosolic and the chloroplastic antioxidant isozymes[integral of] using two different ozone-exposure protocols.
Cytosolic protein kinase C also gets activated upon EPEC infection and translocates to the plasma membrane (28).
Ethanol (ethyl alcohol) is principally oxidized in the liver, primarily by the
cytosolic enzyme, alcohol dehydrogenase (ADH), to acetaldehyde and then to acetate[1].