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Noun

deoxythymidine monophosphate - one of the four nucleotides used in building DNA; all four nucleotides have a common phosphate group and a sugar (ribose)

nucleotide, base - a phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA)

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References in periodicals archive

In folate pathway mechanism deoxythymidine monophosphate (dTMP) (dTMP) is produced from deoxyuridine monophosphate (dUMP) by oxidation of tetrahydrofolate to dihydrofolate catalysed by dihydrofolate reductase (DHFR) (Hyde 2005; Abali et al.

Identification of Novel Dihydrofolate Reductase Inhibitor as Potential Antimalarial Drug: In silico Studies

In this reaction, one carbon group of the 5,10-MTHF is transferred to a molecule called deoxyuridine monophosphate (dUMP), resulting in the formation of deoxythymidine monophosphate (dTMP) and dihydrofolate (DHF).

Alcohol, DNA methylation, and cancer

Thymidylate synthase (TS) is a homodimer of approximately 72 kDa which catalyzes the reductive methylation of 2-deoxyuridine monophosphate (dUMP) using 5,10-methylenetetrahydrofolate ([CH.sub.2][H.sub.4]folate) to form deoxythymidine monophosphate (dTMP) and dihydrofolate ([H.sub.2]folate).

Stabilization of the Inactive Conformation of Human Thymidylate Synthase

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