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Noun

diethylstilbesterol - synthetic nonsteroid with the properties of estrogen; formerly used to treat menstrual problems but was found to be associated with vaginal cancers in the daughters of women so treated during pregnancy

nonsteroid, nonsteroidal - an organic compound that does no contain a steroid

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References in periodicals archive

We have seen this for CVS vs amnio cytogenetics, diethylstilbesterol cancer risks, choroid plexus cysts, intracardiac echogenic focus, and numerous others ultrasound markers.

Emerging Considerations for Noninvasive Prenatal Testing

Worsening of the disease with pregnancy, oral contraceptive use, in postmenopausal women on combination of estrogen and progesterone for osteoporosis, male patients receiving diethylstilbesterol for prostate cancer, (5,6) points to hormonal etiology of melasma.

Clinico epidemiological and biochemical profile of patients with melasma

Hsp90 and environmental impacts on epigenetic states: a model for the trans-generational effects of diethylstilbesterol on uterine development and cancer.

New exposure biomarkers as tools for breast cancer epidemiology, biomonitoring, and prevention: a systematic approach based on animal evidence

A dose dependent increasing trend was observed for gnestein supplemented birds.Isoflavones have a common diphenolicstructure that resembles the potent synthetic estrogen diethylstilbesterol and hexestrol (Tham et al., 1998).

Evaluation of Genistein Mediated Growth, Metabolic and Anti- Inflammatory Responses in Broilers

Phytoestrogens are natural phytochemicals, which are found in plants and their products, and are structurally and functionally similar to oestradiol-17b (isoflavone) or synthetic estrogens such as diethylstilbesterol (lignine).

Effects of Medicago sativa on Some Serum Biochemical Metabolites in Rats

BPA is often described as a weak estrogen because the dose needed to stimulate breast-cancer cell growth is 100,000 times higher than estradiol, the main estrogen receptor found on breast cancer cells.4 However, BPA has been shown to alter cell function and prolactin secretion at very low doses, less than 1 part per trillion.4 Despite BPA's having lower estrogenicity than estradiol, in in vivo studies its estrogenicity is only 100-fold lower than that of diethylstilbesterol (DES).

Environmental medicine update: breast cancer and Bisphenol A