In chronic TBI patients with
diffuse axonal injury, metabolic decreases are pronounced in the frontal cortex, temporal cortex, thalamus, and cerebellum and the severity of frontal lobe hypometabolism is related to cognitive function [335].
Axonal injury, often termed
diffuse axonal injury (DAI), is a common consequence of brain injury and is associated with poor outcomes (Bramlett & Dalton, 2004).
Diffusion imaging can also aid in the evaluation of closed head injury with suspected axonal shearing, with higher sensitivity to
diffuse axonal injury (DAI) lesions than either fast spin-echo T2-weighted imaging or gradient echo [T2.sup.*]-weighted imaging when patients are imaged within 48 hours of injury.
Such damage, known as
Diffuse Axonal Injury (DAI), can only occur, it is believed, if severe force is applied.
MRI is superior to CT scan for helping identify
Diffuse Axonal Injury (DAI) and small intraparenchymal contusions.
Bianchi has been diagnosed with a
diffuse axonal injury to the brain whereby damage has occurred over a widespread area.
Pathologist Dr Tuomo Polvikoski said Mr Kajun died from facial and skull fractures and subdural hematoma, caused by
diffuse axonal injury, consistent with injuries sustained from the a fall.
The most common micro-bleed mimics seen on MRI include mineral deposits, flow voids, bone/air artifacts, cavernous malformations, metastatic melanoma, and
diffuse axonal injury.
The resulting axonal strain injuries, collectively referred to as
diffuse axonal injury (DAI), represent the primary fundamental neuropathological change seen in TBI due to closed mechanisms regardless of injury severity, although the amount of DAI increases as injury severity increases [5].
These findings were in agreement with reporting's of Zimmerman showing CT incidence of 3 -15% of
diffuse axonal injury. All of which were confirmed in post mortem.
There is controversy around the old idea that shaking and/or angular deceleration injuries cause
diffuse axonal injury (DAI), Dr.
DIFFUSE BRAIN INJURY: Depending upon serverity of impact, head injury could lead to minor concussion or
diffuse axonal injury. A concussion is temporary loss of neurological function immediately after trauma with no radiological findings and associated with complete recovery.