References in periodicals archive

[alpha]7, alpha-7 nicotinic receptor; CB1, cannabinoid receptor type 1; CN, Calcineurin; DAO, D-amino acid oxidase; DISC1, Disrupted-In-Schizophrenia 1; DTNBP1, Dysbindin; ErbB4, Erythroblastic leukemia viral oncogene homolog 4; FMRP, fragile X mental retardation protein; G72 (also known as D-amino acid oxidase activator); Kal-7, Kalirin-7; mGluR, metabotropic glutamate receptor; NL, Neuroligin; NR1, NMDA-R, NR1 Subunit; NR2, NMDA-R, NR2 Subunit, NRG1, Neuregulin 1; PICK1, protein kinase C alpha binding protein.

Synaptic functions and their disruption in schizophrenia: From clinical evidence to synaptic optogenetics in an animal model

Other genes proposed in 2005 by Harrison and Weinberger included G72, D-amino acid oxidase (DAO), regulator of G-protein signalling 4 (RGS4), proline dehydrogenase (PRODH), mGluR3, disrupted in schizophrenia 1 (DISC1), COMT, NRG1 and dystrobrevin-binding protein 1(dysbindin, or DTNBP1).

Association between a single nucleotide polymorphism in neuregulin-1 and schizophrenia in Pakistani patients

[37] showed that antipsychotic drugs attenuated the aberrant DNA methylation of the dysbindin (BTNBP1) promoter in the saliva and postmortem brain samples of patients with schizophrenia and psychotic bipolar disorder.

Effects of Antipsychotic Drugs on the Epigenetic Modification of Brain-Derived Neurotrophic Factor Gene Expression in the Hippocampi of Chronic Restraint Stress Rats

In this respect, it should be evident that among some of the most researched gene candidates such as DTNBP1 (dysbindin), NRG1 (neuregulin), RGS4 (G-protein signalling 4) provide only minor and subtle clues as to what is their involvement in the etiology of schizophrenia, as well as any issues relating to genetic risk factors (Allen et al, 2008).

UNDERSTANDING THE NATURE AND AETIOLOGY OF SCHIZOPHRENIA

(25) Studies in humans have identified a gene called dysbindin on chromosome 6 and another called SNAP-25 on chromosome 20 that are associated with cognitive ability.

Ethical, legal, social, and policy issues in the use of genomic technology by the U.S. military

TRIM32 is an E3 ubiquitin ligase for dysbindin. Hum Mol Genet 2009;18:2344-58.

Epidemiology and genetics of osteoarthritis

"We know that in schizophrenia this ability is reduced, and now, knowing more about why this happens may help explain how loss of a protein called dysbindin leads to some symptoms of schizophrenia."

Schizophrenia Linked to Disruption in How Brain Processes Sound

The susceptibility genes with the strongest evidence are dystrobrevin binding protein 1 or dysbindin (DTNB1) and neuregulin 1 (NRG1).

First-episode psychosis: an update

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.

Esquizofrenia y neurodesarrollo

Consistent evidence has been gathered that supports a role for the gene that codes for dysbindin in schizophrenia.

Genetic susceptibility to psychiatric disorders

Genetic Variation in the 6p22.3 Gene DTNBPI, the Human Ortholog of the Mouse Dysbindin Gene, is Associated with Schizophrenia.

Genetica de la esquizofrenia: avances en el estudio de genes candidatos