os·si·fi·ca·tion

(ŏs′ə-fĭ-kā′shən)

1. The natural process of bone formation.

a. The hardening or calcification of soft tissue into a bonelike material.

b. A mass or deposit of such material.

a. The process of becoming set in a rigidly conventional pattern, as of behavior, habits, or beliefs.

b. Rigid, unimaginative convention.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ossification

(ˌɒsɪfɪˈkeɪʃən)

1. (Anatomy) the formation of or conversion into bone

2. the process of ossifying or the state of being ossified

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

os·si·fi·ca·tion

(ŏs′ə-fĭ-kā′shən)

The process of bone formation, brought about by the action of specialized bone cells called osteoblasts.

The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun	1.	ossification - the developmental process of bone formation biological process, organic process - a process occurring in living organisms
	2.	ossification - the calcification of soft tissue into a bonelike material calcification - a process that impregnates something with calcium (or calcium salts)
	3.	ossification - the process of becoming rigidly fixed in a conventional pattern of thought or behavior human process - a process in which human beings are involved
	4.	ossification - hardened conventionality conformity conventionalism, conventionality, convention - orthodoxy as a consequence of being conventional

Translations

ossificazione

ossification

[ˌɒsɪfɪˈkeɪʃən] N → osificación f

Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 1971, 1988 © HarperCollins Publishers 1992, 1993, 1996, 1997, 2000, 2003, 2005

ossification

n → Verknöcherung f, → Ossifikation f (spec)

Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

ossification

[ˌɒsɪfɪˈkeɪʃ/ən] n → ossificazione f (fig) (of ideas) → fossilizzazione f

Collins Italian Dictionary 1st Edition © HarperCollins Publishers 1995

os·si·fi·ca·tion

n. osificación, proceso de desarrollo óseo.

n. osificación.

1. conversión de una sustancia en hueso;

2. desarrollo del hueso.

English-Spanish Medical Dictionary © Farlex 2012

Mentioned in

References in periodicals archive

Blount disease, also known as tibia vara, is caused by abnormal endochondral ossification of the medial aspect of the proximal tibial physis.

Musculoskeletal imaging in children: What the general radiologist should know

Growth of cranial base is mainly due to endochondral ossification. With age the dental effect increases and skeletal effect decreases.9 Present study targeted the patients with skeletal malocclusions.

ASSOCIATION OF MAXILLARY AND MANDIBULAR UNIT LENGTH WITH SKELETAL MALOCCLUSION

The more than 200 bones in the human body are formed during embryonic and postnatal skeletogenesis by two distinct, well-organized processes: intramembranous and endochondral ossification.

Scientists Identify Mechanism For Generating Skeleton

They ossify by the process of endochondral ossification with a small portion ossifying in membrane.

ANATOMICAL STUDY OF FORAMEN VESALIUS

OC may occur on any bone in which endochondral ossification develops.

Solitary Osteochondroma of the Ventral Scapula Associated with Large Bursa Formation and Pseudowinging of the Scapula: A Case Report and Literature Review

Secondly, no areas of endochondral ossification are seen in the histologic examination of the transformed tissue as it would be expected in developing fetal bone [5].

Osseous Metaplasia of the Cervix: A Rare Transformation Can Mimic a Tumor--Literature Review

studied 22 central nervous system and musculoskeletal mesenchymal chondrosarcomas and found that 67% of cases demonstrated acquired osteoblastic phenotype, cells positive for osteocalcin at the site of endochondral ossification [18].

The Role of Osteocalcin and Alkaline Phosphatase Immunohistochemistry in Osteosarcoma Diagnosis

Among the most significant were pathways involved in the regulation of the actin cytoskeleton, focal adhesion signaling, endochondral ossification, TGF[beta]1 signaling, regulation of the microtubule cytoskeleton, and MAPK signaling (Figure 6(b)).

TGF[beta]1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton

This interaction plays an important role in endochondral ossification at the level of the growth plate, an important component of longitudinal bone growth [6].

Heterozygous NPR2 Mutation in Two Family Members with Short Stature and Skeletal Dysplasia

(2003) found an increase in chondrocyte hypertrophy of the chondrogenic layer, increased endochondral ossification and a marked increase in Metabolic activity in the group treated with LIPUS.

Effects of Underwater Lipus on the Morphohistology of the CF-1 Mice Growth Plate in Late Lactation Stage/ Efectos del Ultrasonido Subacuatico Sobre la Morfohistologia de la Placa de Crecimiento de Ratones CF-1 en Etapa de Lactancia Tardia