Animals were killed by
etherization. Evaluation of immune state included determination of relative content of T- and B- lymphocytes (CD3+, CD20+lymphocytes), immune regulatory lymphocytes T-helpers/inductors (CD4) and Tcytotoxic/suppressors (CD8), natural killers (CD16) by a method of indirect rosetteformation (Zalyalieva, 2004; Cheredeev, Gorlina and Kozlov, 1999) by using of monoclonal antibodies of "ICO" series (MedBioSpectr, Russia), determination of phagocytosis activity of neutrophils (PhAN) and circulating immune complexes (CIC).