A synthetic estrogen derivative, C20H24O2, used in oral and other contraceptive preparations and in hormone replacement therapy, usually in combination with a progestin.
[ethinyl, variant of ethynyl, containing an acetylene group : ethyn(e) + -yl.]
"If there is clinical significance, we need to think about whether the appropriate dose of ethynyl estradiol for teens may be 35 mcg and whether the trade-off with the risk of VTE--which is relatively small in adolescents--is acceptable." Other questions include whether and to what degree bone mass recovery occurs after cessation of these agents and whether lifestyle factors, including nutrition and physical activity, can override some of the negative bone effects.
"If there is clinical significance, we need to think about whether the appropriate dose of ethynyl estradiol for teens may be 35 mcg and whether the trade-off with the risk of VTE--which is relatively small in adolescents--is acceptable." It also needs to be clarified whether bone mass recovery occurs after cessation of these agents and whether lifestyle factors can override some of the negative bone effects, she said.
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