This identified a child who arrived recently from India, was treated for viral
exanthema, and discharged.
Clinicaln drug allergies Organ specific Clinical findings reactions Skin
Exanthema, urticaria/ angioedema, drug eruption, pustules, bulleous lesions, SJS, TEN, cutaneous lupus Hematologic Hemolytic anemia, thrombocytopenia, granulocytopenia Liver Hepatitis, cholestatic jaundice Lung Pneumoniae, fibrosis Kidney Intestitial nephritis, membraneous glomerulonephritis Multiple organ reactions Anaphylaxis Urticaria/ angioedema, bronchospasm, gastrointesitnal system symptoms, hypotension DRESS Skin eruptions, fever, eosinophilia, hepatic failure, lymphadenopathy Serum sickness Urticaria, arthralgia, fever SLE Arthralgia, myalgia, fever, weakness Vasculitis Cutaneous or visceral SJS: Stevens-Johnson syndrome TEN: Toxic epidermal necrolysis
The rash may evolve into a vesiculobullous and rarely a purpuric
exanthema, particularly in children.
The most common signs of illness in the patients admitted to the UOHC were polyarthralgia,
exanthema, myalgia, headache, and fever.
If the early
exanthema of acute GVHD displays erythematous follicular papules showing folliculotropic infiltrates accompanied by basal vacuolization and satellite cell necrosis, the papules might help distinguish severe acute GVHD from TEN [14].
The erythematous rash appears as an asymmetrical or unilateral papular, scarlatiniform, or eczematous
exanthema. It initially affects the axilla or groin and may then progress to the extremities and trunk.
These vesicles can be caused by a handful of diseases - including FMD, vesicular stomatitis, swine vesicular disease, and vesicular
exanthema - known collectively as vesicular diseases.
In temperate climates, this highly contagious virus has a seasonal prevalence in winter and spring.[1] Chickenpox is associated with a widespread vesicular
exanthema that occurs without respect to dermatomal distribution (Figure 1) and has been well recognized by parents and pediatricians alike for more than 100 years.
Most common was a combination of
exanthema, urticarial eruptions, lichenoid skin lesions, and purpura.
The most reported side effects with Sib use are infections (22%), flu-like symptoms (14%), headaches (14%), appetite increase (14%), pharingitis (13%), dry mouth (9%), constipation (9%), hypertension (8%), insomnia (8%), abdominal pain (8%), back ache (8%),
exanthema (7%), asthenia (7%), nausea (7%), depression (6%), and other less frequent symptoms (16).
Patients can present with diffuse
exanthema, and other systemic abnormalities are common.