free nerve ending

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Noun1.free nerve ending - microscopic sensory nerve endings in the skin that are not connected to any specific sensory receptor
cutis, skin, tegument - a natural protective body covering and site of the sense of touch; "your skin is the largest organ of your body"
nerve end, nerve ending - the terminal structure of an axon that does not end at a synapse
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Additionally, it decreases free nerve ending sensitivity and increases nerve firing thresholds and slow down the synaptic activity.
COMPARISON OF COLD-GEL PACK THERAPY WITH ORAL IBUPROFEN FOR THE PAIN RELIEF BEFORE INTRALESIONAL INJECTION OF TRIAMCINOLONE ACETONIDE IN THE TREATMENT OF KELOIDS
Skin Receptor Frequency Meissner corpuscle 1-300 Hz Glabrous skin Merkel cell 0-100 Hz Free nerve ending 0-8 Hz Pacinian corpuscle 5-1000 Hz Hairy skin Merkel cell Hair flattening Skin Nerve Modality A[beta](RA1-LTMR) Stroking Fluttering Glabrous skin A[beta](SA1-LTMR) Pressure Texture -- -- A[beta](RA2-LTMR) Vibration Hairy skin A[beta](SA1-LTMR) A[delta] (SA1-LTMR) RA: rapid adaptation; SA: slow adaptation; LTMR: low-threshold mechanoreceptor.
A Proposed Molecular Mechanism for Physical Analgesia in Chronic Pain
Approximately 80% of afferent information about our periphery comes from free nerve endings that terminate between the cords and fibrils of fascia throughout the body.
The Truth About Pain--A Different Paradigm
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