gam·ma-hy·drox·y·bu·ty·rate

(găm′ə-hī-drŏk′sē-byo͞o′tə-rāt′)

n. Abbr. GHB

A compound, C₄H₈O₃, similar in structure and function to gamma-aminobutyric acid, usually used in the form of its sodium salt. It is prescribed to treat certain symptoms of narcolepsy and is used illegally for its euphoric and sedative effects.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Translations

gamma-hydroxybutyrate, gamma-hydroxybutyric acid (GHB)

n gamma-hidroxibutirato, ácido gamma hidroxi-butírico, éxtasis líquido (fam)

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References in periodicals archive

[USA], Oct 9 (ANI): According to a new research, regular use of the party drug GHB (Gamma-hydroxybutyrate), which is often placed in alcoholic beverages, is associated with brain changes including negative effects on long-term memory, working memory, IQ, and higher levels of stress and anxiety.

This drug may affect your IQ!

GHB stands for gamma-Hydroxybutyrate drug, commonly known as liquid ecstasy or simply, 'G.'

PNP to update rape prevention guidelines

A detailed history of past or current substance use was obtained, including cannabis, MDMA (methylenedioxymethamphetamine), GHB (gamma-hydroxybutyrate), crystal methamphetamine, cocaine, CAT (methcathinone), liquid MDMA (liquid E), heroin and methaqualone.

Hepatitis C prevalence in HIV-infected heterosexual men and men who have sex with men

Baclofen, a GABA-B agonist, similar to phenibut, blocks voltage-gated calcium channels; however it does not have affinity for the gamma-hydroxybutyrate (GHB) receptor; therefore abuse potential is minimal [9].

Phenibut ([beta]-Phenyl-[gamma]-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse

(NASDAQ: ALDX) presented novel data at the American Society of Human Genetics 2017 annual meeting demonstrating that ADX-102 reduced levels of gamma-hydroxybutyrate (GHB) and gamma-aminobutyrate (GABA) in a knockout mouse model of Succinic Semialdehyde Dehydrogenase (SSADH) deficiency, the company said.

Aldeyra Therapeutics Data Show ADX-102 Reduces GHB and GABA in Mouse Model of SSADH Deficiency

Drugs commonly involved as date-rape drugs are hypnotic or can lead to amnesia: benzodiazepines, gamma-hydroxybutyrate and its derivates or ketamine (Scott-Ham & Burton 2005; Hurley, Parker & Wells 2006; Jansen & Theron 2006).

A case of drug-facilitated sexual assault involving 3,4-methylene-dioxy-methylamphetamine

Biopharmaceutical company Jazz Pharmaceuticals plc (NasdaqGSJAZZ) revealed on Tuesday the receipt of the US patent related to the use of Xyrem (sodium oxybate) oral solution for the treatment of narcolepsy, titled 'Microbiologically Sound and Stable Solutions of Gamma-Hydroxybutyrate Salt for the Treatment of Narcolepsy'.

Jazz Pharmaceuticals plc receives additional Xyrem patent for the treatment of narcolepsy

These include 3,4 methylenedioxymethamphetamine (MDMA or ecstasy), gamma-hydroxybutyrate (GHB) and ketamine.

Emergency management of drug abuse in South Africa: drug abuse remains both a global scourge and a significant social and medical problem in South Africa

(1) In this article we focus on G, the collective term for gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL).

The silent "G": a case study in the production of "drugs" and "drug problems"

National Institute on Drug Abuse (NIDA) in its "Community Alert on Club Drugs," defined "club drugs" as Ecstasy (3,4-methylenedioxymethamphetamine, or MDMA), gamma-hydroxybutyrate (GHB), ketamine, Rohypnol (flunitrazepam), methamphetamine, and lysergic acid diethylamide (LSD) (3).

Club drugs: review of the 'rave' with a note of concern for the Indian scenario