vac·cin·i·a

(văk-sĭn′ē-ə)

2. The usually mild, cutaneous and sometimes systemic reaction in individuals who have been inoculated with smallpox vaccine.

[New Latin vaccīnia, from Latin vaccīnus, of cows; see vaccine.]

vac·cin′i·al adj.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

vaccinia

(vækˈsɪnɪə)

(Veterinary Science) a technical name for cowpox

[C19: New Latin, from Latin vaccīnus of cows]

vacˈcinial adj

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

vac•cin•i•a

(vækˈsɪn i ə)

n., pl. -cin•i•as.

a variant of the cowpox virus that became established in vaccines derived from cowpox-inoculated humans.

[1800–10]

vac•cin′i•al, adj.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun	1.	vaccinia - a local infection induced in humans by inoculation with the virus causing cowpox in order to confer resistance to smallpox; normally lasts three weeks and leaves a pitted scar vaccina, variola vaccina, variola vaccine, variola vaccinia progressive vaccinia, vaccinia gangrenosa - a severe or even fatal form of vaccinia that occurs mainly in persons with an immunological deficiency; characterized by progressive enlargement of the initial lesion infection - the pathological state resulting from the invasion of the body by pathogenic microorganisms
	2.	vaccinia - a viral disease of cattle causing a mild skin disease affecting the udder; formerly used to inoculate humans against smallpox cowpox pox - a contagious disease characterized by purulent skin eruptions that may leave pock marks animal disease - a disease that typically does not affect human beings

Translations

vac·cin·i·a

n. vaccinia, virus causante de la viruela bovina del cual se obtiene la vacuna contra la viruela.

English-Spanish Medical Dictionary © Farlex 2012

vaccinia

n vacuna

Mentioned in

References in periodicals archive

Adverse reactions to vaccinia vaccination range from mild and self-limited to severe and life-threatening, including inoculation site signs and symptoms, constitutional symptoms, generalized vaccinia, eczema vaccinatum, and progressive vaccinia (1,3).

Adverse reaction after vaccinia virus vaccination--New Mexico, 2016

Early diagnosis is essential for differentiating cowpox from illnesses and skin reactions with similar signs and symptoms, such as smallpox, monkeypox, generalized vaccinia virus infection, disseminated herpes zoster and herpes simplex virus infections, drug-associated eruptions, erythema multiforme, enterovirus infections, secondary syphilis, scabies, insect bites, impetigo, and molluscum contagiosum.

Generalized cowpox virus infection in a patient with HIV, Germany, 2012

Some other well-documented complications of smallpox vaccination that date back to the era of routine smallpox vaccination include generalized vaccinia, eczema vaccinatum, postvaccinial encephalitis, inadvertent inoculation, fetal vaccinia, and death.

New smallpox vaccine backed for high-risk needs

An immunoglobulin containing antivaccinia antibody for the treatment and/or modification of serious complications of smallpox vaccination, including eczema vaccinatum, progressive vaccinia, severe generalized vaccinia, and vaccinia infections in people who have skin conditions, such as burns, impetigo, or varicella zoster.

Vaccinia Immune Globulin, Atacand

"Folliculitis following smallpox vaccination appears distinct from earlier descriptions of generalized vaccinia," Dr.

Folliculitis common after smallpox vaccination: from papules to pustules without scarring

* Generalized vaccinia. Vesicles or pustules may appear on normal skin distant from the vaccination site, usually 6-9 days after vaccination, and often be accompanied by fever, headache, and myalgia.

Smallpox adverse reactions cover broad range. (Mild Lesions Reassuring)

Other common adverse reactions likely to result in either ambulatory visits or time lost from work or school include a robust primary reaction (4% to 18%); generalized vaccinia (240 out of 1 million primary vaccinations) with vesicles/pustules distant from vaccine site and mild systemic illness; inadvertent inoculation to other places on the body (529 out of 1 million); eczema vaccinia (1 out of 25,000) generally occurring among persons with a history of eczema; progressive vaccinia (1 out of 600,000) seen among persons with impaired T-cell function with necrosis at the vaccine site, with severe and potentially fatal systemic illness.

Vaccines and bioterrorism: smallpox and anthrax