ghrelin

Also found in: Medical, Wikipedia.

ghrel·in

 (grĕl′ən)
n.
A hormone that is secreted by cells in the stomach and promotes hunger before an expected meal, decreases in amount after eating, and promotes secretion of growth hormone.
[Coined by its discoverers from ghrē-, reconstructed Proto-Indo-European root of English grow; see grow + -in (probably influenced by g(rowth)-h(ormone)-rel(easing peptide), a description of ghrelin's function and chemical composition).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ghrelin

(ˈɡrɛlɪn)
n
(Biochemistry) a hormone produced in the body that stimulates appetite
[C20: from g(rowth) h(ormone) rel(easing) + -in]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ghrelin - a gastrointestinal hormone produced by epithelial cells lining the fundus of the stomach; appears to be a stimulant for appetite and feeding, but is also a strong stimulant of growth hormone secretion from the anterior pituitary
gastrointestinal hormone, GI hormones - hormones that affect gastrointestinal functioning
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Mentioned in
References in periodicals archive
After centrifugation of blood sample, these were analysed for ghrelin hormone levels by using full-automated ELISA.
COMPARISON OF GHRELIN HORMONE AMONG PREGNANT SUDANESE WOMEN
Ghrelin is an acylated peptide which contains 28 amino acids and it is primarily produced in the stomach and the proximal small intestine (4).
Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects
Ghrelin, one of the hormones playing a role in the pathogenesis of IBS, is a 28-amino acid lipopeptide hormone produced in the enteroendocrine X/A-like cells of the gastric oxyntic gland mucosa (6).
Relationship between irritable bowel syndrome and plasma and tissue ghrelin levels
Two hormones, leptin and ghrelin, are known to trigger the body to eat in a weight-loss setting.
Weight loss linked with active self-control
Ghrelin Improves the Fine Structure of Atrial Natriuretic Factor (ANF) Granules and Intercalated Disc Junctions in Experimentally-Induced Myocardial Infarction in Rats
La Grelina Mejora las Estructuras Finas de los Granulos de Factor Natriuretico Atrial (ANF) y las Uniones Intercaladas de Disco en el Infarto de Miocardio Inducido Experimentalmente en Ratas
Interstitial cells of Cajal (ICC), expression of stem cell factor (SCF), ghrelin, and endothelin-1 play important roles in intestinal motility (12-14).
TNF-[alpha] inhibits SCF, ghrelin, and substance P expressions through the NF-[kappa]B pathway activation in interstitial cells of Cajal
RM-853 is a potent, orally available ghrelin o-acyltransferase inhibitor currently in preclinical development for Prader-Willi Syndrome.
Rhythm Pharmaceuticals announces licensing agreement with Takeda
Ghrelin, the endogenous ligand for the GH-secretagogue receptor (GHS-R), has been found in the testes of many vertebrates, and in the cerebellum and gastrointestinal tract of African ostrich, but there is little known about its distribution in the testes of the African ostrich.
Distribution and Morphology of Ghrelin-Immunopositive Cells in the Testes of the African Ostrich
Ghrelin, originally identified as a growth hormone secretagogue with orexigenic and lipogenic effects, has also been shown to play significant roles in glucose regulation.
Assessment of Salivary Adipokines Resistin, Visfatin, and Ghrelin as Type 2 Diabetes Mellitus Biomarkers
In physiological conditions, ghrelin levels raise in anticipation of a meal and decrease during the postprandial period [19].
Altered feeding behaviors and adiposity precede observable weight gain in young rats submitted to a short-term high-fat diet
Cholecystokinin also acts to decrease the hunger-promoting hormone in the body called ghrelin.
Keeping Hunger at Bay: Combat hunger with a few simple diet strategies
Copyright © 2003-2025 Farlex, Inc Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.