Systemic therapies--which, when studied, have been given at tinea capitis doses--could include
griseofulvin, terbinafine, itraconazole, and fluconazole.
The patient's medical history was significant for a scalp lesion (FIGURE 1) that was being treated with oral
griseofulvin (started 3 days earlier).
Primary analytical reference standards with purity > 99% of ciprofloxacin (CPF), trimethoprim (TMP), sulphamethoxazole (SMZ), metronidazole (MTZ), amoxicillin (AMX), clavulanic acid (CLA), flucloxacillin (FCX), cefuroxime (CFX), arthemether (ART), lumefantrine (LUM), mebendazole (MBZ), albendazole (ALB), ferrous ammonium citrate (FAC), vitamin B1 (VB1), vitamin B3 (VB3), vitamin B6 (VB6), folic acid (FLA),
griseofulvin (GFV), paracetamol (PCM), and ibuprofen (IBF) were obtained from the Food and Drugs Authority, Ghana.
Nystatin and
griseofulvin were used as the positive control for fungus Fusarium oxysporum.
[20] Earlier days
Griseofulvin was the drug of choice for tinea infections, but gradually the relapse rate increased and thus Terbinafine was pushed to the forefront for the treatment of Tinea corporis/Tinea cruris.
Griseofulvin was found effective against Aspergillus, Trichophyton, Microsporum species, while strains of Zygomycetes and Candida spp.
The comparison between the activities of antifungal drugs (
griseofulvin) showed that the leaves and bark extracts of C.
Examples include naproxen, nifedipine, danazol,
griseofulvin, phenytoin, indomethacin, aluminium oxide, titanium oxide, lithium carbonate and iron phosphate.
Griseofulvin 1, a natural product from Penicillium griseofulvum, was first discovered in 1939 and has been known for its antifungal properties in guinea pigs and man since 1958 [1-4].
In a randomized controlled study, subclinical hepatic dysfunction was observed in 17.5% of patients treated with ketoconazole while none of the patients treated with
griseofulvin had evidence of hepatic dysfunction [11].
Rifampin and
griseofulvin are the only antibiotics known to decrease the contraceptive effect of the medications.
Miconazole, systemic antifungal agent
Griseofulvin (8mg/kg b.wt.), topical Tr.